Recombinant Human CXCL10 (C-Fc-6His)(Cat. No.:CX32) novoprotein
$95.00
In stock
SKU
CX32
10μg: $95
50μg: $285
500μg: $1540
1mg: $2200
Description
Recombinant Human C-X-C Motif Chemokine 10 is produced by our Mammalian expression system and the target gene encoding Val22-Pro98 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.
Product Details
| Item | Details |
| Known As | C-X-C Motif Chemokine 10; 10 kDa Interferon Gamma-Induced Protein; Gamma-IP10; IP-10; Small-Inducible Cytokine B10; CXCL10; INP10; SCYB10 |
| Mol Mass | 36.6 KDa |
| APMol Mass | 35 KDa, reducing conditions |
| Formulation Description | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Background
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity.
title: Spatiotemporal dynamics of CXCL10 encode contextual immune information revealed by the genetically encoded fluorescent sensor
authors: Fengxue Xi, Chenyu Wang, Yuanxia Wang, Pengwei Luan, Yue Chen, Luqiao Tan, Nianhan Shang, Xinwei Gao, Daoming Chen, Qingchun Guo, Ting Chen, Miao Jing
date: 2025/08/15
journal: IMMUNITY
title: CXCL10 Produced by HPV-Positive Cervical Cancer Cells Stimulates Exosomal PDL1 Expression by Fibroblasts via CXCR3 and JAK-STAT Pathways
authors: Xiaona Chen, Hui He, Yue Xiao, Ayshamgul Hasim, Jianlin Yuan, Min Ye, Xin Li, Yi Hao, Xia Guo
date: 2021
journal: Frontiers in Oncology
MDSD
Reviews
Write Your Own Review