Recombinant Human CXCL5(Cat. No.:CF14) novoprotein
$95.00
In stock
SKU
CF14
10μg: $95
50μg: $285
500μg: $1540
1mg: $2200
Description
Recombinant Human C-X-C Motif Chemokine 5 is produced by our E.coli expression system and the target gene encoding Leu44-Asn114 is expressed.
Product Details
| Item | Details |
| Known As | C-X-C Motif Chemokine 5; ENA-78 (1-78); Epithelial-Derived Neutrophil-Activating Protein 78; Neutrophil-Activating Peptide ENA-78; Small-Inducible Cytokine B5; ENA-78 (8-78); ENA-78 (9-78); CXCL5; ENA78; SCYB5 |
| Mol Mass | 7.95 KDa |
| APMol Mass | 8 KDa, reducing conditions |
| Formulation Description | Lyophilized from a 0.2 μm filtered solution of 20mM Citrate，8% Trehalose，4% Mannitol，50mM NaCl，0.05% Tween 80，pH 5.0. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Background
C-X-C Motif Chemokine 5 (CXCL5) is a member of the Intercrine Alpha (Chemokine CXC) family. CXCL5 can be cleaved into the following two chains, ENA-78 (8-78) and ENA-78 (9-78). In vitro, ENA-78(8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. CXCL5 is a secreted protein and exercises the functions primarily through interactions with CXCR2. The upregulation of CXCL5 contributes to increased vascularization, tumor grown, and metastasis in many cancers.
title: L1CAM deployed perivascular tumor niche promotes vessel wall invasion of tumor thrombus and metastasis of renal cell carcinoma
authors: Wu Zonglong, Wu Yaqian, Liu Zhuo, Song Yimeng, Ge Liyuan, Du Tan, Liu Yunchong, Liu Li, Liu Cheng, Ma Lulin
date: 2023
journal: Cell Death Discovery
title: CXCL5 promotes lipotoxicity of hepatocytes through upregulating NLRP3/Caspase-1/IL-1β signaling in Kupffer cells and exacerbates nonalcoholic steatohepatitis in mice
authors: Jing Qi, Xueqing Yan, Lanqian Li, Kexin Qiu, Weizhi Huang, Zixiong Zhou
date: 2023
journal: INTERNATIONAL IMMUNOPHARMACOLOGY
title: Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine
authors: Hao-Xiang Yuan, Cai-Yun Chen, Yu-Quan Li, Da-Sheng Ning, Yan Li, Ya-Ting Chen, Shang-Xuan Li, Meng-Xia Fu, Xiao-Di Li, Jian Ma, Yu-Peng Jian, Dong-Hong Liu, Zhi-Wei Mo, Yue-Ming Peng, Kang-Qing Xu, Zhi-Jun Ou, Jing-Song Ou
date: 2020
journal: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
MDSD
Reviews
Write Your Own Review