Recombinant Human IFNGR1 (C-6His)(Cat. No.:CI70) novoprotein
$50.00
In stock
SKU
CI70
10μg: $50
50μg: $105
500μg: $650
1mg: $1050
Description
Recombinant Human Interferon Gamma Receptor 1 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser245 is expressed with a 6His tag at the C-terminus.
Product Details
| Item | Details |
| Known As | Interferon gamma receptor 1; IFNGR1; CDw119; CD119 |
| Mol Mass | 26.8 KDa |
| APMol Mass | 40-50 KDa, reducing conditions |
| Formulation Description | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| Shipping | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Background
Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
title: Chip-DSF: A rapid screening strategy for drug protein targets
authors: Zhao Cui, Peng Chen, Caifeng Li, Shiwen Deng, Hongjun Yang
date: 2022
journal: PHARMACOLOGICAL RESEARCH
MDSD
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