NOTCH2(Cleaved-Ala1734) Antibody Blocking Peptide solarbio K110834P-Ag
$120.00
In stock
SKU
K110834P-Ag
Storage:Store at -20℃,2 years.Avoid freeze/thaw cycles.
| Gene ID:4853 | Application:Blocking Peptide of K110834P Antibody |
| K110834P-Ag-500ug | $120.00 |
| Name NOTCH2(Cleaved-Ala1734) Antibody Blocking Peptide | Appearance Lyophilized powder |
| Source Synthetic | Storage Store at -20℃,2 years.Avoid freeze/thaw cycles. |
| Specification 500ug | Swiss Prot Q04721 |
| Gene ID 4853 | Application Blocking Peptide of K110834P Antibody |
| Purification Method HPLC | Background Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus (PubMed:21378985, PubMed:21378989). Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation (PubMed:29149593). Positively regulates self-renewal of liver cancer cells (PubMed:25985737). |
| Biological Activity Not tested | 1.The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas. 2.For your safety and health, please wear laboratory clothes, disposable gloves and masks. 3.The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation. |
| biogegep10 | biogegep20 |