volume::125mL×4
| Form::Liquid | Bacteria Detection::Negative |
| Fungi Detection::Negative | Mycoplasma Detection::Negative |
| Endotoxin Content:: | pH::7.4-7.8 |
| Components::MEM, with NEAA [PM150410]+10% Nutrient+1% Supplement | Green Features::Sustainable packaging |
| Valid Period::6 months | Storage Condition::This product can be stored at 2-8℃ for 6 months with shading light. |
| Matters Need Attention::1. This product is for research use only. 2. This product is sterilized by 0.1 μm filtration. 3. It is necessary to pay attention to the aseptic operation and avoid the contamination during the culture. 4. It is not suitable for long time storage at room temperature. 5. This product is a ready-to-use medium. If there is no special need, don't add serum, penicillin and streptomycin. It can be used directly. | System Certification::GMP Production and Quality System The company complies with cGMP requirements, holds the NMPA medical device registration certificate, and is certified under ISO 13485 and ISO 9001 standards. Among its products, the company's HK-2 Cell Complete Medium complies with ISO 9001. |
| biogegep7 | biogegep17 |
| biogegep8 | biogegep18 |
| biogegep9 | biogegep19 |
| biogegep10 | biogegep20 |
Title: Keratin 18 functions as a lactyltransferase to trigger necroptosis in diabetic kidney disease by modulating Fas transcription
Journal: EXPERIMENTAL AND MOLECULAR MEDICINE (2026)
IF: 17.5
DOI: 10.1038/s12276-026-01737-9
Article URL: https://www.nature.com/articles/s12276-026-01737-9
Product Cited: HK-2 Cells Line, Human Glomerular Endothelial Cell Complete Medium, HK-2 Cell Complete Medium, Human Glomerular Endothelial Cells
Title: A Rsv@HMnO2-HA nanozyme for AKI therapy via targeting inflammatory storm and activating SIRT1/PGC-1α to restore mitochondrial homeostasis
Journal: Journal of Advanced Research (2026)
IF: 13
DOI: 10.1016/j.jare.2026.03.029
Article URL: https://www.sciencedirect.com/science/article/pii/S209012322600250X
Product Cited: HK-2 Cell Complete Medium, HK-2 Cells Line
Title: Sea cucumber peptides alleviate hyperuricemic nephropathy via HIF-1α/NF-κB/STAT3-SIRT1/p300 axis-mediated metabolic and epigenetic modulation
Journal: Food & Function (2026)
IF: 5.4
DOI: 10.1039/D5FO05202E
Article URL: https://pubs.rsc.org/en/content/articlelanding/2026/fo/d5fo05202e
Product Cited: HK-2 Cell Complete Medium, MEM Medium, HK-2 Cells Line
Title: DNA hypermethylation of FGFR2 drives fibrosis in the aging kidney
Journal: Scientific Reports (2026)
IF: 4.9
DOI: 10.1038/s41598-026-51208-4
Article URL: https://www.nature.com/articles/s41598-026-51208-4
Product Cited: HK-2 Cell Complete Medium, HK-2 Cells Line
Title: Combining bioinformatics and machine learning to analyze and validate sepsis-related cell senescence genes and potential drugs
Journal: RENAL FAILURE (2026)
IF: 3.8
DOI: 10.1080/0886022X.2026.2667584
Article URL: https://www.tandfonline.com/doi/abs/10.1080/0886022X.2026.2667584
Product Cited: HK-2 Cell Complete Medium, HK-2 Cells Line
Title: Regulation of sepsis-associated acute kidney injury by ELAVL1 through USP14/NCOA4-mediated ferroptosis in renal tubular epithelial cells
Journal: MOLECULAR AND CELLULAR BIOCHEMISTRY (2026)
IF: 3.7
DOI: 10.1007/s11010-026-05533-x
Article URL: https://link.springer.com/article/10.1007/s11010-026-05533-x
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: PGAM1 Orchestrates Cell Cycle Progression, Glycolytic Reprogramming, and Immunosuppressive Microenvironment in Triple-Negative Breast Cancer
Journal: IUBMB LIFE (2026)
IF: 3.2
DOI: 10.1002/iub.70109
Article URL: https://iubmb.onlinelibrary.wiley.com/doi/abs/10.1002/iub.70109
Product Cited: HK-2 Cell Complete Medium, MDA-MB-231 Cells Line, BT-549 Cells Line, HCC1937 Cells Line, MCF 10A Cells Line
Title: Transcriptome and weighted gene co-expression network analysis identify hub genes and pathways in rat kidneys after deep hypothermic circulatory arrest
Journal: RENAL FAILURE (2026)
IF: 3
DOI: 10.1080/0886022X.2026.2635286
Article URL: https://www.tandfonline.com/doi/abs/10.1080/0886022X.2026.2635286
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: Hirudin Attenuates Uric Acid-Induced Renal Tubular Injury via TNFRSF6B-Mediated Suppression of NF-κB Signaling
Journal: Pharmacology Research & Perspectives (2026)
IF: 2.6
DOI: 10.1002/prp2.70305
Article URL: https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1002/prp2.70305
Product Cited: HK-2 Cell Complete Medium
Title: AARS1-mediated lactylation of H3K18 and STAT1 promotes ferroptosis in diabetic nephropathy
Journal: CELL DEATH AND DIFFERENTIATION (2025)
IF: 15.4
DOI: 10.1038/s41418-025-01587-4
Article URL: https://www.nature.com/articles/s41418-025-01587-4
Product Cited: Human Glomerular Endothelial Cells, HK-2 Cells Line, HK-2 Cell Complete Medium, Human Glomerular Endothelial Cell Complete Medium
Title: IGF1R Enhances Calcium Oxalate Monohydrate-Induced Epithelial-Mesenchymal Transition by Reprogramming Metabolism via the JAK2/STAT3 Signaling
Journal: International Journal of Biological Sciences (2025)
IF: 8.2
DOI: 10.7150/ijbs.104311
Article URL: https://www.ijbs.com/v21p0415.htm
Product Cited: HK-2 Cell Complete Medium, HK-2 Cells Line
Title: PRPF19 mediates the proteasomal degradation of VDR to exacerbate ferroptosis in diabetic nephropathy
Journal: Cell Communication and Signaling (2025)
IF: 8.2
DOI: 10.1186/s12964-025-02253-5
Article URL: https://link.springer.com/article/10.1186/s12964-025-02253-5
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: Caffeic acid phenethyl ester protects renal tubular epithelial cells against ferroptosis in diabetic kidney disease via restoring PINK1-mediated mitophagy
Journal: MOLECULAR MEDICINE (2025)
IF: 6.4
DOI: 10.1186/s10020-025-01318-y
Article URL: https://link.springer.com/article/10.1186/s10020-025-01318-y
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: Bioinformatics analysis and experimental validation of potential targets and pathways in chronic kidney disease associated with renal fibrosis
Journal: Journal of Translational Medicine (2025)
IF: 6.1
DOI: 10.1186/s12967-024-06058-x
Article URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC11967072/
Product Cited: HK-2 Cell Complete Medium
Title: Multi-omics analysis identifies UBA family as potential pan-cancer biomarkers for tumor prognosis and immune microenvironment infiltration
Journal: Frontiers in Immunology (2025)
IF: 5.7
DOI: 10.3389/fimmu.2025.1510503
Article URL: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1510503/full
Product Cited: SW480 [SW-480] Cell Complete Medium, SW620 Cell Complete Medium, 769-P Cell Complete Medium, HK-2 Cell Complete Medium, Caki-1 Cell Complete Medium, 786-O [786-0] Cell Complete Medium
Title: Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of Guben Xiezhuo decoction against renal fibrosis
Journal: Scientific Reports (2025)
IF: 3.9
DOI: 10.1038/s41598-025-16012-6
Article URL: https://www.nature.com/articles/s41598-025-16012-6
Product Cited: HK-2 Cell Complete Medium, HK-2 Cells Line
Title: Molecular interplay between TXNIP and GLUT9 underlies uric acid transport dysregulation in vitro under hyperuricemic stress
Journal: EUROPEAN JOURNAL OF MEDICAL RESEARCH (2025)
IF: 3.4
DOI: 10.1186/s40001-025-03209-8
Article URL: https://eurjmedres.biomedcentral.com/articles/10.1186/s40001-025-03209-8
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: P110 Inhibits DRP1/FIS1-Mediated Mitochondrial Fission to Alleviate Uric Acid–Induced Apoptosis in HK-2 Cells
Journal: Frontiers in Bioscience-Landmark (2025)
IF: 3.1
DOI: 10.31083/FBL46700
Article URL: https://www.imrpress.com/journal/FBL/30/11/10.31083/FBL46700/htm
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: Solute carrier family 1 member 1 in renal interstitial fibrosis: evaluating its influence on glutamate uptake and extracellular ion levels
Journal: Frontiers in Medicine (2025)
IF: 3
DOI: 10.3389/fmed.2025.1694428
Article URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC12753501/
Product Cited: HK-2 Cells Line, MEM (without glutamic acid), HK-2 Cell Complete Medium, TGFB1/TGFβ1/TGF-β1, Human, Recombinant
Title: M6A methyltransferase ZC3H13-mediated downregulation of GPX4 mRNA stability inhibits the progression of kidney renal clear cell carcinoma (KIRC)
Journal: CELLULAR IMMUNOLOGY (2025)
IF: 2.9
DOI: 10.1016/j.cellimm.2025.104998
Article URL: https://www.sciencedirect.com/science/article/pii/S000887492500084X
Product Cited: Caki-1 Cell Complete Medium, 293T [HEK-293T] Cells Line, ACHN Cell Complete Medium, 786-O [786-0] Cells Line, ACHN Cells Line, 786-O [786-0] Cell Complete Medium, Caki-1 Cells Line, HK-2 Cells Line, HK-2 Cell Complete Medium, 769-P Cell Complete Medium, 769-P Cells Line
Title: Characterizing Chemokine Signaling Pathways and Hub Genes in Calcium Oxalate-Induced Kidney Stone Formation: Insights from Rodent Models
Journal: BIOCHEMICAL GENETICS (2025)
IF: 2.1
DOI: 10.1007/s10528-025-11036-z
Article URL: https://link.springer.com/article/10.1007/s10528-025-11036-z
Product Cited: HK-2 Cell Complete Medium, HK-2 Cells Line
Title: The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy
Journal: CELL DEATH AND DIFFERENTIATION (2024)
IF: 13.7
DOI: 10.1038/s41418-024-01357-8
Article URL: https://www.nature.com/articles/s41418-024-01357-8
Product Cited: Human Glomerular Endothelial Cell Complete Medium, HK-2 Cells Line, HK-2 Cell Complete Medium, Human Glomerular Endothelial Cells
Title: An enzyme-mimicking reactive oxygen species scavenger targeting oxidative stress-inflammation cycle ameliorates IR-AKI by inhibiting pyruvate dehydrogenase kinase 4
Journal: Theranostics (2024)
IF: 12.4
DOI: 10.7150/thno.101229
Article URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC11626943/
Product Cited: HK-2 Cell Complete Medium, RAW 264.7 Cell Complete Medium
Title: Fasn involved in the nephrotoxicity induced by polystyrene nanoplastics and the intervention of melatonin through intestinal microbiota-mediated lipid metabolism disorder
Journal: Nano Research (2024)
IF: 9.5
DOI: 10.1007/s12274-024-6610-9
Article URL: https://link.springer.com/article/10.1007/s12274-024-6610-9
Product Cited: HK-2 Cell Complete Medium
Title: A precise dual-drug codelivery nanosystem for treating kidney failure by eliminating senescent cells
Journal: Science China-Materials (2024)
IF: 6.8
DOI: 10.1007/s40843-024-2864-5
Article URL: https://link.springer.com/article/10.1007/s40843-024-2864-5
Product Cited: HK-2 Cell Complete Medium
Title: Dexmedetomidine inhibits ferroptosis and attenuates sepsis-induced acute kidney injury via activating the Nrf2/SLC7A11/FSP1/CoQ10 pathway
Journal: REDOX REPORT (2024)
IF: 5.2
DOI: 10.1080/13510002.2024.2430929
Article URL: https://www.tandfonline.com/doi/abs/10.1080/13510002.2024.2430929
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis
Journal: TOXICOLOGY (2024)
IF: 4.8
DOI: 10.1016/j.tox.2024.153996
Article URL: https://www.sciencedirect.com/science/article/pii/S0300483X24002774
Product Cited: HK-2 Cell Complete Medium
Title: Polystyrene microplastics facilitate renal fibrosis through accelerating tubular epithelial cell senescence
Journal: FOOD AND CHEMICAL TOXICOLOGY (2024)
IF: 3.9
DOI: 10.1016/j.fct.2024.114888
Article URL: https://www.sciencedirect.com/science/article/pii/S027869152400454X
Product Cited: HK-2 Cell Complete Medium
Title: CircVMA21-related pathway alleviates lipopolysaccharide-induced HK-2 cell injury
Journal: SHOCK (2024)
IF: 2.7
DOI: 10.1097/SHK.0000000000002364
Article URL: https://journals.lww.com/shockjournal/abstract/9900/circvma21_related_pathway_alleviates.412.aspx
Product Cited: 293T [HEK-293T] Cells Line, HK-2 Cell Complete Medium, HK-2 Cells Line
Title: Cytosolic mtDNA–cGAS–STING axis contributes to sepsis-induced acute kidney injury via activating the NLRP3 inflammasome
Journal: Clinical and Experimental Nephrology (2024)
IF: 2.3
DOI: 10.1007/s10157-023-02448-5
Article URL: https://link.springer.com/article/10.1007/s10157-023-02448-5
Product Cited: HK-2 Cells Line, HK-2 Cells Complete Medium
Title: Plasma exosomes may mediate the development of lupus nephritis in patients with systemic lupus erythematosus
Journal: LUPUS (2024)
IF: 1.9
DOI: 10.1177/09612033241298047
Article URL: https://journals.sagepub.com/doi/abs/10.1177/09612033241298047
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: Inhibition of intrarenal PRR-RAS pathway by Ganoderma lucidum polysaccharide peptides in proteinuric nephropathy
Journal: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)
IF: 8.2
DOI: 10.1016/j.ijbiomac.2023.127336
Article URL: https://www.sciencedirect.com/science/article/pii/S0141813023042332
Product Cited: HK-2 Cells Line, HK-2 Cells Complete Medium
Title: Melatonin alleviates intrarenal CaOx crystals deposition through inhibiting LPS-induced non-canonical inflammasome-mediated renal tubular epithelial cells pyroptosis
Journal: INTERNATIONAL IMMUNOPHARMACOLOGY (2023)
IF: 5.6
DOI: 10.1016/j.intimp.2023.110796
Article URL: https://www.sciencedirect.com/science/article/pii/S1567576923011219
Product Cited: HK-2 Cells Line, HK-2 Cells Complete Medium
Title: Ferroptosis in calcium oxalate kidney stone formation and the possible regulatory mechanism of ANKRD1
Journal: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2023)
IF: 5.1
DOI: 10.1016/j.bbamcr.2023.119452
Article URL: https://www.sciencedirect.com/science/article/pii/S016748892300023X
Product Cited: HK-2 Cells Line, HK-2 Cells Complete Medium
Title: CD72, a new immune checkpoint molecule, is a novel prognostic biomarker for kidney renal clear cell carcinoma
Journal: EUROPEAN JOURNAL OF MEDICAL RESEARCH (2023)
IF: 4.2
DOI: 10.1186/s40001-023-01487-8
Article URL: https://eurjmedres.biomedcentral.com/articles/10.1186/s40001-023-01487-8
Product Cited: HK-2 Cell Complete Medium
Title: Integrative analysis of transcriptome and metabolome provide new insights into mechanisms of Capilliposide A against cisplatin-induced nephrotoxicity
Journal: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2023)
IF: 3.4
DOI: 10.1016/j.jpba.2023.115814
Article URL: https://www.sciencedirect.com/science/article/pii/S0731708523005836
Product Cited: HK-2 Cells Complete Medium, MEM
Title: Panax notoginseng Saponins Alleviate LPS-induced Fibrosis of HK-2 Cells by Inhibiting the Activation of NLRP3 Inflammasome and Pyroptosis
Journal: CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2023)
IF: 2.8
DOI: 10.2174/1389201024666230417084507
Article URL: https://www.ingentaconnect.com/content/ben/cpb/pre-prints/content-37073148
Product Cited: HK-2 Cells Line, HK-2 Cell Complete Medium
Title: Shen Qi Wan-Containing Serum Alleviates Renal Interstitial Fibrosis via Restraining Notch1-Mediated Epithelial-Mesenchymal Transition
Journal: Evidence-based Complementary and Alternative Medicine (2023)
IF: 2.7
DOI: 10.1155/2023/3352353
Article URL: https://www.hindawi.com/journals/ecam/2023/3352353/
Product Cited: HK-2 Cells Line, HK-2 Cells Complete Medium
Title: Ufl1 deficiency causes skin pigmentation by up-regulation of Endothelin-1
Journal: Frontiers in Cell and Developmental Biology (2022)
IF: 6.081
DOI: 10.3389/fcell.2022.961675
Article URL: https://www.frontiersin.org/articles/10.3389/fcell.2022.961675/full
Product Cited: HK-2 Cell Complete Medium
Title: Identification of Prognostic Metabolism-Related Genes in Clear Cell Renal Cell Carcinoma
Journal: Journal of Oncology (2021)
IF: 4.5
DOI: 10.1155/2021/2042114
Article URL: https://www.hindawi.com/journals/jo/2021/2042114/
Product Cited: HK-2 Cells Complete Medium
Title: Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis
Journal: Journal of Genetics and Genomics (2021)
IF: 4.275
DOI: 10.1016/j.jgg.2021.04.006
Article URL: https://www.sciencedirect.com/science/article/pii/S1673852721001028
Product Cited: HK-2 Cell Complete Medium