Anti-Mouse CD11b (M1/70) Rat Recombinant Antibody 65672-1-TR proteintech
$59.00
In stock
SKU
65672-1-TR
| Catalog Number | 65672-1-TR |
| Synonyms | CR3, CR3A, integrin alpha M, Itgam, Ly 40 |
| Host | Rat |
| Reactivity | Human,Mouse,Cynomolgus monkey,Guinea pig,Rabbit |
| Reactivity | human, mouse, cynomolgus monkey, guinea pig, rabbit |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Rat / IgG2a |
| Tested Applications — Positive FC detected in | mouse bone marrow cells, rabbit splenocytes, human PBMCs |
| Positive FC detected in | mouse bone marrow cells, rabbit splenocytes, human PBMCs |
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | Human,Mouse,Cynomolgus monkey,Guinea pig,Rabbit |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | N/A Predict reactive species |
| Full Name | integrin alpha M |
| Calculated Molecular Weight | 127 kDa |
| GenBank Accession Number | BC156991 |
| Gene Symbol | CD11b |
| Gene ID (NCBI) | 16409 |
| RRID | AB_3743290 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | E9Q604 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
| FC protocol for CD11b antibody 65672-1-TR | Download protocol |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | M1/70 |
| Conjugation | Unconjugated |
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828). Protocols Product Specific Protocols FC protocol for CD11b antibody 65672-1-TR Download protocol Standard Protocols Click here to view our Standard Protocols
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