Anti-Mouse IFNGR1/CD119 Rabbit Recombinant Antibody 98201-1-RR proteintech
$59.00
In stock
SKU
98201-1-RR
| Catalog Number | 98201-1-RR |
| Synonyms | IFN-gamma-R-alpha, IFN-gamma-R1, IFN-gamma receptor 1, IFN-gamma R1, CD119 |
| Host | Rabbit |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | mouse splenocytes |
| Positive FC detected in | mouse splenocytes |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Recombinant protein Predict reactive species |
| Full Name | interferon gamma receptor 1 |
| Calculated Molecular Weight | 52kDa |
| GenBank Accession Number | NM_010511.3 |
| Gene Symbol | Ifngr1 |
| Gene ID (NCBI) | 15979 |
| RRID | AB_3745871 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | P15261 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
| FC protocol for IFNGR1/CD119 antibody 98201-1-RR | Download protocol |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 241832H4 |
| Conjugation | Unconjugated |
Interferon-gamam (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113) Protocols Product Specific Protocols FC protocol for IFNGR1/CD119 antibody 98201-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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