FcZero-rAb® APC Anti-Human CD44 (F10-44-2) Rabbit Recombinant Antibody APC-FcA65608 proteintech
$252.00
In stock
SKU
APC-FcA65608
| Catalog Number | APC-FcA65608 |
| Synonyms | CD44 antigen, CDW44, CSPG8, ECMR III, ECMR-III |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | N/A Predict reactive species |
| Full Name | CD44 molecule (Indian blood group) |
| Calculated Molecular Weight | 742 aa, 82 kDa |
| GenBank Accession Number | BC004372 |
| Gene Symbol | CD44 |
| Gene ID (NCBI) | 960 |
| ENSEMBL Gene ID | ENSG00000026508 |
| RRID | AB_3746444 |
| Conjugate | APC Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 650 nm / 660 nm |
| Excitation Laser | Red Laser (633 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P16070 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for APC CD44 antibody APC-FcA65608 | Download protocol |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | F10-44-2 |
| Conjugation | APC |
CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Protocols Product Specific Protocols FC protocol for APC CD44 antibody APC-FcA65608 Download protocol Standard Protocols Click here to view our Standard Protocols
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