FcZero-rAb® APC Anti-Mouse CD8a Rabbit Recombinant Antibody APC-FcA98472-2 proteintech
$76.00
In stock
SKU
APC-FcA98472-2
| Catalog Number | APC-FcA98472-2 |
| Synonyms | CD8, CD8 antigen, alpha chain, CD8α, Ly 2, Ly 35 |
| Host | Rabbit |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | mouse splenocytes |
| Positive FC detected in | mouse splenocytes |
| Flow Cytometry (FC) | FC : 0.1 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | mouse |
| Cited Reactivity | mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg3265 Product name: Recombinant Mouse CD8A protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 28-196 aa of NM_001081110.2 Sequence: KPQAPELRIFPKKMDAELGQKVDLVCEVLGSVSQGCSWLFQNSSSKLPQPTFVVYMASSHNKITWDEKLNSSKLFSAMRDTNNKYVLTLNKFSKENEGYYFCSVISNSVMYFSSVVPVLQKVNSTTTKPVLRTPSPVHPTGTSQPQRPEDCRPRGSVKGTGLDFACDIY Predict reactive species |
| Full Name | CD8 antigen, alpha chain |
| Calculated Molecular Weight | 27 kDa |
| GenBank Accession Number | NM_001081110.2 |
| Gene Symbol | Cd8a |
| Gene ID (NCBI) | 12525 |
| RRID | AB_3746647 |
| Conjugate | APC Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 650 nm / 660 nm |
| Excitation Laser | Red Laser (633 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P01731 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for APC CD8a antibody APC-FcA98472-2 | Download protocol |
| mouse | FC Vet Microbiol Synthetic peptide vaccines targeting SVA elicit robust protective immune responses in swine. Authors - Yamei Li View Article |
| Citations | 4 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 242879C10 |
| Conjugation | APC |
CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells, on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084). Protocols Product Specific Protocols FC protocol for APC CD8a antibody APC-FcA98472-2 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Discovery of natural product-derived rosavin as a programmed death-ligand 1 inhibitor for cancer immunotherapy.
Journal: Phytomedicine | Authors: Wei Zou | Species: mouse | Application: FC - Self-Assembled Nanoparticle Vaccines Elicit Robust Protective Immune Responses against Type O Foot-and-Mouth Disease Virus Infection.
Journal: ACS Nano | Authors: Nan Cao | Species: mouse | Application: FC - Synthetic peptide vaccines targeting SVA elicit robust protective immune responses in swine.
Journal: Vet Microbiol | Authors: Yamei Li | Species: mouse | Application: FC - TALDO1 promotes lipid metabolic reprogramming and immunosuppressive microenvironment remodelling in hepatocellular carcinoma
Journal: Clin Transl Med | Authors: Fenglin Lv | Application: FC
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