CACNA1S Polyclonal antibody 22279-1-AP proteintech
$149.00
In stock
SKU
22279-1-AP
| Catalog Number | 22279-1-AP |
| Synonyms | CACH1, CACN1, CACNL1A3, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Cav1.1 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | human brain tissue, mouse kidney tissue, rat kidney tissue |
| Tested Applications — Positive IHC detected in | human skeletal muscle tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:1000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| Positive WB detected in | human brain tissue, mouse kidney tissue, rat kidney tissue |
| Positive IHC detected in | human skeletal muscle tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | calcium channel, voltage-dependent, L type, alpha 1S subunit |
| Calculated Molecular Weight | 212 kDa |
| Observed Molecular Weight | 200-220 kDa |
| GenBank Accession Number | NM_000069 |
| Gene Symbol | CACNA1S |
| Gene ID (NCBI) | 779 |
| RRID | AB_2879058 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13698 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for CACNA1S antibody 22279-1-AP | Download protocol |
| WB protocol for CACNA1S antibody 22279-1-AP | Download protocol |
| human | WB bioRxiv Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM Authors - Jorge L Jimenez-Macias View Article |
| Citations | 2 |
| Dilutions | WB : 1:500-1:1000 IHC : 1:20-1:200 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
CACNA1S, also named as CACH1, CACN1 and CACNL1A3, belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family and CACNA1S subfamily. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. CACNA1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. The antibody is specific to CACNA1S. Protocols Product Specific Protocols IHC protocol for CACNA1S antibody 22279-1-AP Download protocol WB protocol for CACNA1S antibody 22279-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Deep RNA sequencing analysis of syncytialization-related genes during BeWo cell fusion.
Journal: Reproduction | Authors: Ru Zheng | Species: human | Application: IHC - Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM
Journal: bioRxiv | Authors: Jorge L Jimenez-Macias | Species: human | Application: WB
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