CCNL1 Polyclonal antibody 13138-1-AP proteintech
$149.00
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SKU
13138-1-AP
| Catalog Number | 13138-1-AP |
| Synonyms | ania 6a, BM 001, BM-001, Cyclin L, cyclin L1 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | COLO 320 cells, MCF-7 cells, PC-3 cells, MDA-MB-231 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:1000 |
| Positive WB detected in | COLO 320 cells, MCF-7 cells, PC-3 cells, MDA-MB-231 cells |
| Western Blot (WB) | WB : 1:500-1:1000 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag3731 Product name: Recombinant human CCNL1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 227-526 aa of BC007081 Sequence: YMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR Predict reactive species |
| Full Name | cyclin L1 |
| Calculated Molecular Weight | 526 aa, 60 kDa |
| Observed Molecular Weight | 46 kDa |
| GenBank Accession Number | BC007081 |
| Gene Symbol | CCNL1 |
| Gene ID (NCBI) | 57018 |
| RRID | AB_10640299 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9UK58 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for CCNL1 antibody 13138-1-AP | Download protocol |
| human | WB Transl Oncol Tumor-derived exosomal miR-199b-5p promotes proliferation and epithelial-mesenchymal transition in non-small cell lung cancer by targeting CCNL1. Authors - Bangzhu Liu KD Validated View Article |
| Citations | 1 |
| Dilutions | WB : 1:500-1:1000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
CCNL1, also named as Cyclin-L1, contains a RS region and belongs to the cyclin family. CCNL1 localizes in the nucleus speckle and is Overexpressed in primary tumors of head and neck squamous cell carcinomas (HNSCC). CCNL1 as transcriptional regulator participates in regulating the pre-mRNA splicing process. It is seems to be involved in the regulation of RNA polymerase II (pol II). CCNL1 functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. It may be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). The calculated molecular weight of CCNL1 is about 55-60 kDa, but we detected a 40-50 kDa isoform by western blotting. Protocols Product Specific Protocols WB protocol for CCNL1 antibody 13138-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Tumor-derived exosomal miR-199b-5p promotes proliferation and epithelial-mesenchymal transition in non-small cell lung cancer by targeting CCNL1.
Journal: Transl Oncol | Authors: Bangzhu Liu KD Validated | Species: human | Application: WB
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