CoraLite®594 Anti-Human CD107b / LAMP2 (H4B4) CL594-65053 proteintech
$175.00
In stock
SKU
CL594-65053
| Catalog Number | CL594-65053 |
| Synonyms | CD107b, LAMP2, CD107 antigen-like family member B, H4B4, LAMP 2 |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | IF/ICC, FC (Intra) |
| Host / Isotype | Mouse / IgG1, kappa |
| Tested Applications — Positive IF/ICC detected in | HeLa cells |
| Tested Applications — Positive FC (Intra) detected in | Jurkat cells |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 5 ul per 10^6 cells in 100 μl suspension |
| Positive IF/ICC detected in | HeLa cells |
| Positive FC (Intra) detected in | Jurkat cells |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 5 ul per 10^6 cells in 100 μl suspension |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Human adherent peripheral blood cells Predict reactive species |
| Full Name | lysosomal-associated membrane protein 2 |
| Calculated Molecular Weight | 45 kDa |
| GenBank Accession Number | BC002965 |
| Gene Symbol | LAMP2 |
| Gene ID (NCBI) | 3920 |
| ENSEMBL Gene ID | ENSG00000005893 |
| RRID | AB_2883469 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Excitation Laser | Yellow-Green Laser (561 nm) |
| Purification Method | Protein G purification |
| UNIPROT ID | P13473 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL594 CD107b / LAMP2 antibody CL594-65053 | Download protocol |
| IF protocol for CL594 CD107b / LAMP2 antibody CL594-65053 | Download protocol |
| human | IF Adv Sci (Weinh) A Novel FGFR3-Targeting Antibody-Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS-STING Pathway in Bladder Cancer. Authors - Shu Cui View Article |
| Citations | 1 |
| Dilutions | IF/ICC : 1:50-1:500 FC (INTRA) : 5 ul per 10^6 cells in 100 μl suspension |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Clone Number | H4B4 |
| Conjugation | CoraLite®594 |
LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may play a role in tumor cell metastasis (PMID 9426697). Protocols Product Specific Protocols FC protocol for CL594 CD107b / LAMP2 antibody CL594-65053 Download protocol IF protocol for CL594 CD107b / LAMP2 antibody CL594-65053 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- A Novel FGFR3-Targeting Antibody-Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS-STING Pathway in Bladder Cancer.
Journal: Adv Sci (Weinh) | Authors: Shu Cui | Species: human | Application: IF
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