FcZero-rAb® CoraLite® Plus 488 Anti-Mouse CD11b (M1/70) Rabbit Recombinant Antibody CL488-FcA65672 proteintech
$167.00
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CL488-FcA65672
| Catalog Number | CL488-FcA65672 |
| Synonyms | CR3, CR3A, integrin alpha M, Itgam, Ly 40 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Cynomolgus monkey,Guinea pig,Rabbit |
| Reactivity | human, mouse, cynomolgus monkey, guinea pig, rabbit |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | mouse bone marrow cells |
| Positive FC detected in | mouse bone marrow cells |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | Human,Mouse,Cynomolgus monkey,Guinea pig,Rabbit |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | N/A Predict reactive species |
| Full Name | integrin alpha M |
| Calculated Molecular Weight | 127 kDa |
| GenBank Accession Number | BC156991 |
| Gene Symbol | CD11b |
| Gene ID (NCBI) | 16409 |
| RRID | AB_3747943 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | E9Q604 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 488 CD11b antibody CL488-FcA65672 | Download protocol |
| Citations | 1 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | M1/70 |
| Conjugation | CoraLite® Plus 488 |
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828). Protocols Product Specific Protocols FC protocol for CL Plus 488 CD11b antibody CL488-FcA65672 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- A low-molecular-weight α-glucan PPS2-A derived from potato starch fermentation by Antarctic Penicillium chrysogenum MS-02: Structural characterization and immunomodulatory activity.
Journal: Int J Biol Macromol | Authors: Fenghua Fan
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