CoraLite® Plus 647 Anti-Human CD11c (3.9) CL647-65086 proteintech
$159.00
In stock
SKU
CL647-65086
| Catalog Number | CL647-65086 |
| Synonyms | CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6 |
| Host | Mouse |
| Reactivity | Human |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Mouse / IgG1, kappa |
| Tested Applications — Positive FC detected in | human peripheral blood monocytes |
| Positive FC detected in | human peripheral blood monocytes |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| Tested Reactivity | Human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Rheumatoid synovial cells and human monocytes Predict reactive species |
| Full Name | integrin, alpha X (complement component 3 receptor 4 subunit) |
| Calculated Molecular Weight | 1169 aa, 129 kDa |
| GenBank Accession Number | BC038237 |
| Gene Symbol | CD11c |
| Gene ID (NCBI) | 3687 |
| ENSEMBL Gene ID | ENSG00000140678 |
| RRID | AB_2883672 |
| Conjugate | CoraLite® Plus 647 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 654 nm / 674 nm |
| Excitation Laser | Red Laser (633 nm) |
| Purification Method | Affinity purification |
| UNIPROT ID | P20702 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 647 CD11c antibody CL647-65086 | Download protocol |
| Citations | - |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Clone Number | 3.9 |
| Conjugation | CoraLite® Plus 647 |
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533). Protocols Product Specific Protocols FC protocol for CL Plus 647 CD11c antibody CL647-65086 Download protocol Standard Protocols Click here to view our Standard Protocols
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