Biotin Anti-Human CD155/PVR (SKII.4) Mouse IgG2a Recombinant Antibody Biotin-65632 proteintech
$159.00
In stock
SKU
Biotin-65632
| Catalog Number | Biotin-65632 |
| Synonyms | PVR, CD155, HVED, Necl 5, NECL5 |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC, ELISA |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | SK-N-AS human neuroblastoma cells Predict reactive species |
| Full Name | poliovirus receptor |
| Calculated Molecular Weight | 45 kDa |
| GenBank Accession Number | BC015542 |
| Gene Symbol | CD155/PVR |
| Gene ID (NCBI) | 5817 |
| RRID | AB_3746754 |
| Conjugate | Biotin |
| Purification Method | Protein A purification |
| UNIPROT ID | P15151 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for Biotin CD155/PVR antibody Biotin-65632 | Download protocol |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | SKII.4 |
| Conjugation | Biotin |
CD155, also known as PVR, is a type I transmembrane glycoprotein in the immunoglobulin superfamily. It contains three extracellular immunoglobulin-like domains, D1-D3, of which D1 is recognized by the virus. Mature human CD155 consists of a 323 amino acid extracellular domain with one N-terminal V-type and two C2-type Ig-like domains, a 24 amino acid transmembrane segment, and a 50 amino acid cytoplasmic tail. CD155 is thought to play a role in adhesion by interaction with the ECM component vitronectin as well as a role in NK killing of tumor cells. CD155 binds to two receptors of NK cells, CD96 and CD226, and accumulates at cell-cell contact sites, leading to the formation of mature immune synapses between NK cells and target cells. CD155 serves as the entry receptor for poliovirus and thereby mediates human susceptibility to poliovirus infection. Protocols Product Specific Protocols FC protocol for Biotin CD155/PVR antibody Biotin-65632 Download protocol Standard Protocols Click here to view our Standard Protocols
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