CoraLite®594 Anti-Human CD16 (3G8) Mouse IgG2a Recombinant Antibody CL594-65612 proteintech
$159.00
In stock
SKU
CL594-65612
| Catalog Number | CL594-65612 |
| Synonyms | 3G8, CD16A, CD16a antigen, CD16-II, Fc gamma RIII |
| Host | Mouse |
| Reactivity | Human,Cynomolgus monkey |
| Reactivity | human, cynomolgus monkey |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive FC detected in | human peripheral blood leukocytes |
| Positive FC detected in | human peripheral blood leukocytes |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| Tested Reactivity | Human,Cynomolgus monkey |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | N/A Predict reactive species |
| Full Name | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
| Calculated Molecular Weight | 254 aa, 29 kDa |
| GenBank Accession Number | BC017865 |
| Gene Symbol | CD16a |
| Gene ID (NCBI) | 2214 |
| ENSEMBL Gene ID | ENSG00000203747 |
| RRID | AB_3748129 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Excitation Laser | Yellow-Green Laser (561 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P08637 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL594 CD16 antibody CL594-65612 | Download protocol |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | 3G8 |
| Conjugation | CoraLite®594 |
CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. Clone 3G8 recognizes both the CD16a and CD16b (PMID: 7592758). Protocols Product Specific Protocols FC protocol for CL594 CD16 antibody CL594-65612 Download protocol Standard Protocols Click here to view our Standard Protocols
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