FcZero-rAb® PE-Cyanine5 Anti-Human CD16 (3G8) Rabbit Recombinant Antibody PY5-FcA65612 proteintech

$214.00
In stock
SKU
PY5-FcA65612
Catalog No.SizePrice (USD)
PY5-FCA65612-100TESTS100tests$214.00
Catalog NumberPY5-FcA65612
Synonyms3G8, CD16A, CD16a antigen, CD16-II, Fc gamma RIII
HostRabbit
ReactivityHuman,Cynomolgus monkey
Reactivityhuman, cynomolgus monkey
FormLiquid
FormulationPBS, Azide, BSA
ApplicationsFC
Host / IsotypeRabbit / IgG
Tested Applications — Positive FC detected inhuman PBMCs
Positive FC detected inhuman PBMCs
Flow Cytometry (FC)FC : 5 ul per 10^6 cells in a 100 µl suspension
Tested ReactivityHuman,Cynomolgus monkey
ClassRecombinant
TypeAntibody
ImmunogenN/A Predict reactive species
Full NameFc fragment of IgG, low affinity IIIa, receptor (CD16a)
Calculated Molecular Weight254 aa, 29 kDa
GenBank Accession NumberBC017865
Gene SymbolCD16a
Gene ID (NCBI)2214
ENSEMBL Gene IDENSG00000203747
RRIDAB_3749920
ConjugatePE-Cyanine5 Fluorescent Dye
Excitation/Emission Maxima Wavelengths496 nm, 565 nm / 666 nm
Excitation LaserBlue Laser (488 nm), Green Laser (532 nm), Yellow-Green Laser (561 nm)
Purification MethodProtein A purification
UNIPROT IDP08637
Storage BufferPBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
FC protocol for PE-Cyanine5 CD16 antibody PY5-FcA65612Download protocol
Citations-
IsotypeIgG
ClonalityRecombinant
Clone Number3G8
ConjugationPE-Cyanine5

CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. Clone 3G8 recognizes both the CD16a and CD16b (PMID: 7592758). Protocols Product Specific Protocols FC protocol for PE-Cyanine5 CD16 antibody PY5-FcA65612 Download protocol Standard Protocols Click here to view our Standard Protocols

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