Anti-Human CD164 Rabbit Recombinant Antibody, PBS Only 98239-1-PBS proteintech

$568.00
In stock
SKU
98239-1-PBS
Catalog No.SizePrice (USD)
98239-1-PBS-1MG1mg$568.00
Custom$0.00
Catalog Number98239-1-PBS
SynonymsMulti-glycosylated core protein 24, MUC-24, MGC-24v, MGC-24, 241950F3
HostRabbit
Reactivityhuman
FormLiquid
FormulationPBS Only
ApplicationsFC
Host / IsotypeRabbit / IgG
Tested Reactivityhuman
ClassRecombinant
TypeAntibody
ImmunogenRecombinant protein Predict reactive species
Full NameCD164 molecule, sialomucin
Calculated Molecular Weight21kDa
GenBank Accession NumberNM_006016.6
Gene SymbolCD164
Gene ID (NCBI)8763
RRIDAB_3745906
ConjugateUnconjugated
Purification MethodProtein A purfication
UNIPROT IDQ04900-1
Storage BufferPBS only, pH 7.3.
Storage ConditionsStore at -80°C.
Citations-
IsotypeIgG
ClonalityRecombinant
Clone Number241950F3
ConjugationUnconjugated

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (PMID: 9680353)(PMID: 17077324). Sialomucin CD164 (MUC-24), also referred to multi-glycosylated core protein 24 (MGC24), is known to function as a receptor that regulates stem cell localization to the bone marrow. CD164 may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. Important role of CD164 in in prostate cancer metastasis, promoting myogenesis and regulating myoblast migration so far have been revealed (PMID: 9763543)(PMID: 16859559)(PMID: 17077324).

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