FcZero-rAb® Biotin Anti-Human CD19 (4G7) Rabbit Recombinant Antibody Biotin-FcA65562 proteintech
$92.00
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SKU
Biotin-FcA65562
| Catalog Number | Biotin-FcA65562 |
| Synonyms | 4G7, B lymphocyte antigen CD19, B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Human chronic lymphocytic leukemia (CLL) cells Predict reactive species |
| Full Name | CD19 molecule |
| Calculated Molecular Weight | 556 aa, 61 kDa |
| GenBank Accession Number | BC006338 |
| Gene Symbol | CD19 |
| Gene ID (NCBI) | 930 |
| ENSEMBL Gene ID | ENSG00000177455 |
| RRID | AB_3746805 |
| Conjugate | Biotin |
| Excitation/Emission Maxima Wavelengths | - |
| Purification Method | Protein A purification |
| UNIPROT ID | P15391 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for Biotin CD19 antibody Biotin-FcA65562 | Download protocol |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 4G7 |
| Conjugation | Biotin |
CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908). Protocols Product Specific Protocols FC protocol for Biotin CD19 antibody Biotin-FcA65562 Download protocol Standard Protocols Click here to view our Standard Protocols
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