CoraLite®594 Anti-Human CD19 (4G7) CL594-65197 proteintech

$159.00
In stock
SKU
CL594-65197
Catalog No.SizePrice (USD)
CL594-65197-100TESTS100tests$159.00
Catalog NumberCL594-65197
SynonymsCD19 molecule, B-lymphocyte surface antigen B4, B-lymphocyte antigen CD19, B4, B lymphocyte antigen CD19
HostMouse
Reactivityhuman
FormLiquid
FormulationPBS, Azide, BSA
ApplicationsFC
Host / IsotypeMouse / IgG1, kappa
Tested Applications — Positive FC detected inhuman PBMCs
Positive FC detected inhuman PBMCs
Flow Cytometry (FC)FC : 5 ul per 10^6 cells in 100 μl suspension
Tested Reactivityhuman
ClassMonoclonal
TypeAntibody
ImmunogenHuman chronic lymphocytic leukemia (CLL) cells Predict reactive species
Full NameCD19 molecule
Calculated Molecular Weight556 aa, 61 kDa
GenBank Accession NumberBC006338
Gene SymbolCD19
Gene ID (NCBI)930
ENSEMBL Gene IDENSG00000177455
RRIDAB_3673465
ConjugateCoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths588 nm / 604 nm
Excitation LaserYellow-Green Laser (561 nm)
Purification MethodProtein G purification
UNIPROT IDP15391
Storage BufferPBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
FC protocol for CL594 CD19 antibody CL594-65197Download protocol
Citations-
IsotypeIgG1, kappa
ClonalityMonoclonal
Clone Number4G7
ConjugationCoraLite®594

CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908). Protocols Product Specific Protocols FC protocol for CL594 CD19 antibody CL594-65197 Download protocol Standard Protocols Click here to view our Standard Protocols

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