FcZero-rAb® PE-Cyanine5.5 Anti-Human CD19 (4G7) Rabbit Recombinant Antibody PY5P5-FcA65562 proteintech

$250.00
In stock
SKU
PY5P5-FcA65562
Catalog No.SizePrice (USD)
PY5P5-FCA65562-100TESTS100tests$250.00
Catalog NumberPY5P5-FcA65562
Synonyms4G7, B lymphocyte antigen CD19, B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4
HostRabbit
Reactivityhuman
FormLiquid
FormulationPBS, Azide, BSA
ApplicationsFC
Host / IsotypeRabbit / IgG
Tested Applications — Positive FC detected inhuman PBMCs
Positive FC detected inhuman PBMCs
Flow Cytometry (FC)FC : 5 ul per 10^6 cells in a 100 µl suspension
Tested Reactivityhuman
ClassRecombinant
TypeAntibody
ImmunogenHuman chronic lymphocytic leukemia (CLL) cells Predict reactive species
Full NameCD19 molecule
Calculated Molecular Weight556 aa, 61 kDa
GenBank Accession NumberBC006338
Gene SymbolCD19
Gene ID (NCBI)930
ENSEMBL Gene IDENSG00000177455
RRIDAB_3749946
ConjugatePE-Cyanine5.5 Fluorescent Dye
Excitation/Emission Maxima Wavelengths496 nm, 565 nm / 692 nm
Excitation LaserBlue Laser (488 nm), Green Laser (532 nm), Yellow-Green Laser (561 nm)
Purification MethodProtein A purification
UNIPROT IDP15391
Storage BufferPBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
FC protocol for PE-Cyanine5.5 CD19 antibody PY5P5-FcA65562Download protocol
Citations-
IsotypeIgG
ClonalityRecombinant
Clone Number4G7
ConjugationPE-Cyanine5.5

CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908). Protocols Product Specific Protocols FC protocol for PE-Cyanine5.5 CD19 antibody PY5P5-FcA65562 Download protocol Standard Protocols Click here to view our Standard Protocols

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