Atlantic Blue™ Anti-Human CD3 (OKT3) AB-65133 proteintech
$159.00
In stock
SKU
AB-65133
| Catalog Number | AB-65133 |
| Synonyms | CD3E, CD3 epsilon, CD3-epsilon, OKT3, T3E |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Mouse / IgG2a, kappa |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Human T cells Predict reactive species |
| Full Name | CD3e molecule, epsilon (CD3-TCR complex) |
| Calculated Molecular Weight | 207 aa, 23 kDa |
| GenBank Accession Number | BC049847 |
| Gene Symbol | CD3 |
| Gene ID (NCBI) | 916 |
| ENSEMBL Gene ID | ENSG00000198851 |
| RRID | AB_2935171 |
| Conjugate | Atlantic Blue™ Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 404 nm / 458 nm |
| Excitation Laser | Violet Laser (405 nm) |
| Purification Method | Affinity purification |
| UNIPROT ID | P07766 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for Atlantic Blue™ CD3 antibody AB-65133 | Download protocol |
| Citations | - |
| Isotype | IgG2a, kappa |
| Clonality | Monoclonal |
| Clone Number | OKT3 |
| Conjugation | Atlantic Blue™ |
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). Protocols Product Specific Protocols FC protocol for Atlantic Blue™ CD3 antibody AB-65133 Download protocol Standard Protocols Click here to view our Standard Protocols
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