FITC Plus Anti-Human CD314/NKG2D (1D11) FITC-65188 proteintech
$172.00
In stock
SKU
FITC-65188
| Catalog Number | FITC-65188 |
| Synonyms | CD314, KLRK1, 1D11, D12S2489E, Killer cell lectin-like receptor subfamily K member 1 |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Mouse / IgG1, kappa |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| Tested Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | NKL cell line Predict reactive species |
| Full Name | killer cell lectin-like receptor subfamily K, member 1 |
| Calculated Molecular Weight | 25 kDa |
| GenBank Accession Number | BC039836 |
| Gene Symbol | KLRK1 |
| Gene ID (NCBI) | 22914 |
| RRID | AB_2883821 |
| Conjugate | FITC Plus Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 498 nm / 526 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| UNIPROT ID | P26718 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for FITC Plus CD314/NKG2D antibody FITC-65188 | Download protocol |
| Citations | - |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Clone Number | 1D11 |
| Conjugation | FITC Plus |
CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In humans, it is expressed on NK cells, gamma delta T cells, and CD8+ alpha beta T cells (PMID: 10426993). Various families of cell surface ligands have been identified, including the MICA/MICB and ULBP proteins (PMID: 12150888). CD314 is involved in both innate and adaptive immunities, and the NKG2D/NKG2DL pathway involves multiple effector cell types for controlling tumor progression (PMID: 31720075). Protocols Product Specific Protocols FC protocol for FITC Plus CD314/NKG2D antibody FITC-65188 Download protocol Standard Protocols Click here to view our Standard Protocols
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