Anti-Rat CD44 Rabbit Recombinant Antibody, PBS Only 98208-1-PBS proteintech
$680.00
In stock
SKU
98208-1-PBS
| Catalog Number | 98208-1-PBS |
| Synonyms | 241648F8, CD44 antigen, ECMR-III, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor |
| Host | Rabbit |
| Reactivity | rat |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | FC |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | rat |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg1458 Product name: Recombinant Rat CD44 protein (rFc Tag) (HPLC verified) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 22-271 aa of XM_006234631.3 Sequence: QQQIDLNITCRYAGVFHVEKNGRYSISRTEAADLCEAFNTTLPTMAQMELALSKGFETCRYGFIEGHVVIPRIHPNAICAANNTGVYILLASNTSHYDTYCFNASAPLEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDIDASNIIDEDVSSGSTIEKSTPEGYILHTDLPTSQPTGDRDDAFFIGSTLATSDGDSSMDPRGGFDTVTHGSELAGHSSGNQDSGVTTTSGPARRPQIPE Predict reactive species |
| Full Name | Cd44 molecule |
| Calculated Molecular Weight | 40 kDa |
| GenBank Accession Number | XM_006234631.3 |
| Gene Symbol | Cd44 |
| Gene ID (NCBI) | 25406 |
| RRID | AB_3745875 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | O70509 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 241648F8 |
| Conjugation | Unconjugated |
CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.
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