| Catalog Number | Biotin-FcA98359-2 |
| Synonyms | CD44 antigen, CDw44, CSPG8, ECMR III, ECMR-III |
| Host | Rabbit |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | mouse splenocytes |
| Positive FC detected in | mouse splenocytes |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg3159 Product name: Recombinant Mouse CD44 protein (rFc Tag) (HPLC verified) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 25-224 aa of NM_009851.2 Sequence: QIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHYDTYCFNASAPPEEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDIDASNIIDDDVSSGSTIEKSTPESYILHTYLPTEQPTGDQDDSFFIRSTLAT Predict reactive species |
| Full Name | CD44 antigen |
| Calculated Molecular Weight | 86 kDa |
| GenBank Accession Number | NM_009851.2 |
| Gene Symbol | Cd44 |
| Gene ID (NCBI) | 12505 |
| RRID | AB_3747048 |
| Conjugate | Biotin |
| Excitation/Emission Maxima Wavelengths | - |
| Purification Method | Protein A purification |
| UNIPROT ID | P15379 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for Biotin CD44 antibody Biotin-FcA98359-2 | Download protocol |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 242666F8 |
| Conjugation | Biotin |
CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Protocols Product Specific Protocols FC protocol for Biotin CD44 antibody Biotin-FcA98359-2 Download protocol Standard Protocols Click here to view our Standard Protocols
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