| Catalog Number | CL488-65578 |
| Synonyms | CD45, Lca, Ptprc, L CA, OX-33 |
| Host | Mouse |
| Reactivity | rat |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive FC detected in | rat splenocytes |
| Positive FC detected in | rat splenocytes |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | rat |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Leukocyte common antigen purified from rat splenocytes Predict reactive species |
| Full Name | protein tyrosine phosphatase, receptor type, C |
| Calculated Molecular Weight | 143 kDa |
| GenBank Accession Number | XM_006249910 |
| Gene Symbol | CD45 |
| Gene ID (NCBI) | 24699 |
| RRID | AB_3672890 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P04157 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 488 CD45RA antibody CL488-65578 | Download protocol |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | OX-33 |
| Conjugation | CoraLite® Plus 488 |
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signaling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RA is expressed on naïve T cells, B cells, and monocytes (PMID: 1830500; 14687231). Protocols Product Specific Protocols FC protocol for CL Plus 488 CD45RA antibody CL488-65578 Download protocol Standard Protocols Click here to view our Standard Protocols
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