| Catalog Number | CR-65167 |
| Synonyms | CD62L, gp90 MEL, hLHRc, L selectin, LAM 1, LAM1, LECAM1, Leu 8, Leukocyte adhesion molecule 1, LNHR, LSEL, Lyam 1, LYAM1, Lymph node homing receptor, PLNHR, selectin L, SELL, TQ1 |
| Host | Mouse |
| Reactivity | Human |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Mouse / IgG1, kappa |
| Tested Applications — Positive FC detected in | human PBMCs |
| Positive FC detected in | human PBMCs |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| Tested Reactivity | Human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | PMA-activated human peripheral blood leukocytes Predict reactive species |
| Full Name | selectin L |
| Calculated Molecular Weight | 42 kDa |
| GenBank Accession Number | BC020758 |
| Gene Symbol | CD62L |
| Gene ID (NCBI) | 6402 |
| ENSEMBL Gene ID | ENSG00000188404 |
| RRID | AB_3084968 |
| Conjugate | Cardinal Red™ Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 592 nm / 611 nm |
| Excitation Laser | Yellow-Green Laser (561 nm) |
| Purification Method | Purified by protein-A affinity chromatography |
| UNIPROT ID | P14151 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for Cardinal Red™ CD62L antibody CR-65167 | Download protocol |
| Citations | - |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Clone Number | DREG56 |
| Conjugation | Cardinal Red™ |
CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078). Protocols Product Specific Protocols FC protocol for Cardinal Red™ CD62L antibody CR-65167 Download protocol Standard Protocols Click here to view our Standard Protocols
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