E2F1 Monoclonal antibody 66515-1-Ig proteintech
$149.00
In stock
SKU
66515-1-Ig
| Catalog Number | 66515-1-Ig |
| Synonyms | 5D7G8, E2F 1, E2F-1, pRB-binding protein E2F-1, RBAP-1 |
| Host | Mouse |
| Reactivity | human, rat and More (1) |
| Reactivity | human, rat, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, IP, CoIP, ChIP, RIP, ELISA |
| Applications | WB, IP, ELISA |
| Host / Isotype | Mouse / IgG2b |
| Tested Applications — Positive WB detected in | LNCaP cells, HepG2 cells, HeLa cells, HEK-293 cells, Jurkat cells, HSC-T6 cells |
| Tested Applications — Positive IP detected in | HEK-293T cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:6000 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Positive WB detected in | LNCaP cells, HepG2 cells, HeLa cells, HEK-293 cells, Jurkat cells, HSC-T6 cells |
| Positive IP detected in | HEK-293T cells |
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Tested Reactivity | human, rat |
| Cited Reactivity | human, mouse, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag17363 Product name: Recombinant human E2F1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 88-438 aa of BC050369 Sequence: VKRRLDLETDHQYLAESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDCDFGDLTPLDF Predict reactive species |
| Full Name | E2F transcription factor 1 |
| Calculated Molecular Weight | 437 aa, 47 kDa |
| Observed Molecular Weight | 55-60 kDa |
| GenBank Accession Number | BC050369 |
| Gene Symbol | E2F1 |
| Gene ID (NCBI) | 1869 |
| RRID | AB_2881878 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q01094 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IP protocol for E2F1 antibody 66515-1-Ig | Download protocol |
| WB protocol for E2F1 antibody 66515-1-Ig | Download protocol |
| human | WB Cell Rep FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression Authors - Yanhua Zhang View Article |
| mouse | WB J Adv Res Transducin-like enhancer of split 3 protects against lipopolysaccharide-induced inflammation through DDX5-ATF1-PPP2R5A signaling Authors - Di Fan View Article |
| Umut (Verified Customer) (08-30-2023) | It works very well, even though it is diluted a lot, i.e., 1:2000. The total protein concentration of my samples were around 2 ug/ml before adding 1:4 laemmli buffer and denature, and it is able to capture the target at low exposure times. Applications: Western Blot Primary Antibody Dilution: 1:2000 Cell Tissue Type: U87MG, glioma-derived E2F1 Antibody Western Blot validation (1:2000 dilution) in U87MG, glioma-derived (Cat no:66515-1-Ig) |
| Juliane (Verified Customer) (05-11-2023) | The antibody worked fine, but only under using ECL sensitve reagent and high exposure when imaging. Applications: Western Blot Primary Antibody Dilution: 1:1000 Cell Tissue Type: HEK293T E2F1 Antibody Western Blot validation (1:1000 dilution) in HEK293T (Cat no:66515-1-Ig) |
| Citations | 101 |
| Dilutions | WB : 1:1000-1:6000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 5D7G8 |
| Conjugation | Unconjugated |
Transcription factor E2F1 (E2F1), also known as RBBP3, is a transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis. The calculated molecular weight of E2F1 is 47 kDa, but the sumoylated E2F1 is bout 55-60 kDa. Protocols Product Specific Protocols IP protocol for E2F1 antibody 66515-1-Ig Download protocol WB protocol for E2F1 antibody 66515-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation
Journal: Dev Cell | Authors: Wanxin Guo | Species: human | Application: WB - LncRNA AGPG confers endocrine resistance in breast cancer by promoting E2F1 activity
Journal: Cancer Res | Authors: Shiyi Yu | Species: human | Application: WB,IF - Transducin-like enhancer of split 3 protects against lipopolysaccharide-induced inflammation through DDX5-ATF1-PPP2R5A signaling
Journal: J Adv Res | Authors: Di Fan | Species: mouse | Application: WB - ZNF652 exerts a tumor suppressor role in lung cancer by transcriptionally downregulating cyclin D3
Journal: Cell Death Dis | Authors: Chunfeng Xie | Species: human | Application: WB - Identification of STAM-binding protein as a target for the treatment of gemcitabine resistance pancreatic cancer in a nutrient-poor microenvironment
Journal: Cell Death Dis | Authors: Wenming Zhang KD Validated | Species: human | Application: WB,IHC,IF,CoIP - FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
Journal: Cell Rep | Authors: Yanhua Zhang | Species: human | Application: WB - MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation
Journal: Nat Commun | Authors: Jian Ma | Species: human | Application: WB - RNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer
Journal: Exp Mol Med | Authors: Xiaoyi Liu | Species: human | Application: WB - Transducin-like enhancer of split 3 protects against lipopolysaccharide-induced inflammation through DDX5-ATF1-PPP2R5A signaling
Journal: J Adv Res | Authors: Di Fan | Species: mouse | Application: WB - Inhibition of METTL14 overcomes CDK4/6 inhibitor resistance driven by METTL14-m6A-E2F1-axis in ERα-positive breast cancer
Journal: J Nanobiotechnology | Authors: Chenlin Liu | Species: human | Application: WB - Druggable target ATAD2 enhances the malignant progression and cooperates with E2F1 to up-regulate PDK1 expression in glioma.
Journal: Genes Dis | Authors: Shenghua Zhuo | Species: human | Application: IHC - Histone modification-regulated LncRNA DLEU1 interacts with ASCC2/ALKBH3 complex to drive DNA repair, antioxidant homeostasis and glucose metabolism in gastric cancer.
Journal: Biomark Res | Authors: Xiaoyan Zhang | Species: human | Application: IHC - E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner
Journal: J Exp Clin Cancer Res | Authors: Jingyuan Li | Application: WB - The Compromised Fanconi Anemia Pathway in Prelamin A-Expressing Cells Contributes to Replication Stress-Induced Genomic Instability
Journal: Adv Sci (Weinh) | Authors: Pengqing Nie | Species: human | Application: WB,IP - Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis
Journal: Adv Sci (Weinh) | Authors: Hyeoncheol Kim | Species: human | Application: WB - DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription
Journal: Cell Rep Med | Authors: Tian Xia - Engineered anchoring aptamers induce relocalization and functional inactivation of transcription factors.
Journal: Sci Adv | Authors: Neng Ling | Species: human | Application: WB,IF - GDPPH1 induces cell cycle arrest by downregulation of CDK4/Cyclin D1 via the m(6)A-METTL14-YTHDF2 axis, attenuating glioblastoma progression.
Journal: Cell Death Dis | Authors: Sijia Li - E2F1 mediated DDX11 transcriptional activation promotes hepatocellular carcinoma progression through PI3K/AKT/mTOR pathway.
Journal: Cell Death Dis | Authors: Yan Yu | Species: human | Application: chIP - Identification of STAM-binding protein as a target for the treatment of gemcitabine resistance pancreatic cancer in a nutrient-poor microenvironment
Journal: Cell Death Dis | Authors: Wenming Zhang | Species: human | Application: WB,IHC,IF,CoIP - CHAC1 blockade suppresses progression of lung adenocarcinoma by interfering with glucose metabolism via hijacking PKM2 nuclear translocation
Journal: Cell Death Dis | Authors: Junfan Pan | Species: human | Application: WB,ChIP - GDPPH1 induces cell cycle arrest by downregulation of CDK4/Cyclin D1 via the m(6)A-METTL14-YTHDF2 axis, attenuating glioblastoma progression.
Journal: Cell Death Dis | Authors: Sijia Li - Chicoric acid targets PYGL to normalize glycogenolysis-driven glycolysis to suppress non-small cell lung cancer.
Journal: Cell Mol Biol Lett | Authors: Xingfa Huo - SMEK1 promotes clear cell Renal Cell Carcinoma progression via EGFR tyrosine-kinase dependent pathway
Journal: Cancer Lett | Authors: Jue Wang | Species: mouse,human | Application: WB,IHC,IF - NEAT1 Promotes the Perineural Invasion of Pancreatic Cancer via the E2F1/GDNF Axis
Journal: Cancer Lett | Authors: Jingtao Gu | Species: human | Application: WB,IHC - Inhibition of IGF2BP1 attenuates renal injury and inflammation by alleviating m6A modifications and E2F1/MIF pathway
Journal: Int J Biol Sci | Authors: Yan Mao | Application: ChIP - Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer.
Journal: Phytomedicine | Authors: Jin-Hua Fan | Species: human | Application: WB - NCOA5 induces sorafenib resistance in hepatocellular carcinoma by inhibiting ferroptosis
Journal: Cell Death Discov | Authors: Shuang Gao | Species: human | Application: WB - Inhibition of USP10 induces myeloma cell apoptosis by promoting cyclin D3 degradation
Journal: Acta Pharmacol Sin | Authors: Yu-Jia Xu | Species: human | Application: WB - RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription
Journal: Cell Death Discov | Authors: Shuai Yang | Species: human | Application: WB,IP - RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription
Journal: Cell Death Discov | Authors: Shuai Yang | Species: human | Application: WB,IP - Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression
Journal: Aging Dis | Authors: Zhengshuai Song | Species: human | Application: WB,ChIP - Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation
Journal: Dev Cell | Authors: Wanxin Guo | Species: human | Application: WB - Oncogene goosecoid is transcriptionally regulated by E2F1 and correlates with disease progression in prostate cancer.
Journal: Chin Med J (Engl) | Authors: Yue Ge | Species: human | Application: ChIP - High-dose copper activates p53-independent apoptosis through the induction of nucleolar stress in human cell lines.
Journal: Apoptosis | Authors: Chieh-Hsin Chen | Species: human | Application: WB - In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis
Journal: Leukemia | Authors: Ngoc Tung Tran | Species: mouse | Application: WB,IP - LncRNA SNHG8 promotes myocardial fibrosis by binding to E2F1 to induce MAD2L1 transcription.
Journal: Int J Biol Macromol | Authors: Lei Huang | Species: mouse, rat | Application: WB - A novel recombinant peptide, rAnguillin, induces ferroptosis in nasopharyngeal carcinoma by promoting FOXM1 degradation and disrupting the FOXM1-PABPC1L-tryptophan metabolism axis.
Journal: Int J Biol Macromol | Authors: Qianhui Yuan | Species: human | Application: WB - Integrated network pharmacology and transcriptomic approach reveal the role of equol in reducing colorectal cancer via regulating multiple cell cycle genes in HCT116 cells
Journal: Int J Biol Macromol | Authors: Kemin Mao | Species: human | Application: WB - KDM1A, a potent and selective target, for the treatment of DNMT3A-deficient non-small cell lung cancer
Journal: Br J Cancer | Authors: Yingxi Zhao | Species: human | Application: ChIP - Restoration of NOX4 signalling reverses endothelial colony-forming cell angiogenic dysfunction associated with experimental and clinical diabetes
Journal: Stem Cell Res Ther | Authors: Karla M O'Neill | Species: human | Application: WB - FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
Journal: Cell Rep | Authors: Yanhua Zhang | Species: human | Application: WB - Talaketides A-G, linear polyketides with prostate cancer cytotoxic activity from the mangrove sediment-derived fungus Talaromyces sp. SCSIO 41027
Journal: Chin J Nat Med | Authors: Chunmei Chen | Species: human - Deapioplatycodin D promotes cell senescence induced by P21 through the mediation of incomplete mitophagy via BNIP3L
Journal: Biomed Pharmacother | Authors: Yiquan Li | Species: human | Application: WB - NSUN2-mediated HCV RNA m5C Methylation Facilitates Viral RNA Stability and Replication
Journal: Genomics Proteomics Bioinformatics | Authors: Zhu-Li Li | Species: human | Application: WB - Interferon regulatory factor 4 mediates nonenzymatic IRE1 dependency in multiple myeloma cells
Journal: PLoS Biol | Authors: Ioanna Oikonomidi | Species: human | Application: WB - Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation.
Journal: Pharmaceutics | Authors: Ting-Syuan Lin | Species: human | Application: WB - Classical prescription Floris Sophorae Powder treat colorectal cancer by regulating KRAS/MEK-ERK signaling pathway
Journal: J Ethnopharmacol | Authors: Li-Ying Han | Species: mouse | Application: WB - Classical prescription Floris Sophorae Powder treat colorectal cancer by regulating KRAS/MEK-ERK signaling pathway
Journal: J Ethnopharmacol | Authors: Li-Ying Han | Species: mouse | Application: WB - The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
Journal: Ecotoxicol Environ Saf | Authors: Zemin Li | Species: human | Application: WB - DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation
Journal: Life Sci | Authors: Linghui Liang | Species: human | Application: WB - E2F1 combined with LINC01004 super-enhancer to promote hepatocellular carcinoma cell proliferation and metastasis
Journal: Clin Epigenetics | Authors: Jingxuan Li | Species: human | Application: WB,ChIP - E2F1-mediated 53BP2 lactylation stabilizes p53 to induce cochlear hair cell apoptosis in mouse age-related hearing loss.
Journal: Clin Epigenetics | Authors: Xiaoqin Luo | Species: mouse | Application: WB - Deficiency of LAMP2A in macrophages accelerates hypoxia-induced atherosclerosis by inhibiting BNIP3-mediated mitophagy.
Journal: Int Immunopharmacol | Authors: Ning Wang - B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
Journal: Cell Oncol (Dordr) | Authors: Ying Lin | Species: human | Application: WB - Analysis of regulating activities of 5'-epiequisetin on proliferation, apoptosis, and migration of prostate cancer cells in vitro and in vivo
Journal: Front Pharmacol | Authors: Xueni Wang | Species: human | Application: WB - RFWD3 Participates in the Occurrence and Development of Colorectal Cancer via E2F1 Transcriptional Regulation of BIRC5.
Journal: Front Cell Dev Biol | Authors: Fenghua Xu | Species: human | Application: IP,ChIP - MASTL Promotes Hepatocellular Carcinoma Progression and Paclitaxel Resistance Through Mitotic Catastrophe.
Journal: Cancer Sci | Authors: Ke Wang | Species: human | Application: WB,ChIP - ARL8B regulates lysosomal function and predicts poor prognosis in hepatocellular carcinoma
Journal: Sci Rep | Authors: Liyan Wu | Species: human | Application: WB - NCAPD2 promotes breast cancer progression through E2F1 transcriptional regulation of CDK1
Journal: Cancer Sci | Authors: Jinsong He | Species: human | Application: CoIP - MASTL Promotes Hepatocellular Carcinoma Progression and Paclitaxel Resistance Through Mitotic Catastrophe.
Journal: Cancer Sci | Authors: Ke Wang | Species: human | Application: WB,ChIP - Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinoma
Journal: J Cell Mol Med | Authors: Xiao-Han Cui | Species: human | Application: WB - TIFA enhances glycolysis through E2F1 and promotes the progression of glioma
Journal: Cell Signal | Authors: Zhibing Liu | Species: human | Application: WB - UCA1 facilitates endometriosis progression through EIF4A3-mediated stabilization of E2F1 mRNA and enhanced glycolysis.
Journal: Cell Signal | Authors: Yingying Cao | Species: human | Application: RIP - TRIB3 promotes endometrial cancer progression through interacting with E2F1 and enhancing PKM2-mediated tumor glycolysis
Journal: Gynecol Oncol | Authors: Feng Geng | Application: IF,ChIP - Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC
Journal: iScience | Authors: Tamara Mirzapoiazova | Species: human | Application: WB - Icaritin inhibits CDK2 expression and activity to interfere with tumor progression
Journal: iScience | Authors: Chao Zhang | Species: human | Application: WB,CoIP - DDB2 promotes melanoma cell growth by transcriptionally regulating the expression of KMT2A and predicts a poor prognosis
Journal: FASEB J | Authors: Changlin Zhang | Species: human | Application: WB - Myricanol Inhibits Platelet Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cells Proliferation and Migration in vitro and Intimal Hyperplasia in vivo by Targeting the Platelet-Derived Growth Factor Receptor-β and NF-κB Signaling.
Journal: Front Physiol | Authors: Siyuan Fan | Species: rat | Application: WB - TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression
Journal: BMC Cancer | Authors: Haodong Wang | Species: human | Application: WB - Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer
Journal: J Biol Chem | Authors: Yingjie Su | Species: human | Application: WB - The acidic microenvironment promotes pancreatic cancer progression via the lncRNA-LOC100507424/E2F1/FOXM1 axis
Journal: BMC Cancer | Authors: Deyang Mu | Application: WB - A novel piperine derivative HJ-23 exhibits anti-colorectal cancer effects by activating the p53 pathway
Journal: Naunyn Schmiedebergs Arch Pharmacol | Authors: Meiqi Zhang | Species: human | Application: WB - NCAPH Promotes the Proliferation of Prostate Cancer Cells Via Modulating the E2F1 Mediated PI3K/AKT/mTOR Axis
Journal: Int J Med Sci | Authors: Qing Shi | Species: human | Application: CoIP,ChIP - KLF11 interacts with MDM2 to stabilize E2F1 and promotes DNA damage repair to induce radioresistance in esophageal cancer cells.
Journal: Pathol Res Pract | Authors: Yaoxiong Xia | Species: human | Application: WB,IHC,IF,CoIP - E2F1-Driven WDHD1 Transcription Enhances Cell-Cycle Progression and Promotes Pancreatic Cancer Progression.
Journal: Curr Oncol | Authors: Xiaojuan Yang | Species: human | Application: ChIP - LncRNA LINC01703 promotes the proliferation, migration, and invasion of colorectal cancer by activating PI3K/AKT pathway
Journal: J Biochem Mol Toxicol | Authors: Yuanhui Xu | Species: human | Application: WB - NAT10 and E2F1 Orchestrate CKAP5-Mediated Progression in Esophageal Squamous Cell Carcinoma.
Journal: J Gastroenterol Hepatol | Authors: Wenxue Wei | Species: human | Application: ChIP - NAT10 and E2F1 Orchestrate CKAP5-Mediated Progression in Esophageal Squamous Cell Carcinoma.
Journal: J Gastroenterol Hepatol | Authors: Wenxue Wei | Species: human | Application: ChIP - FOXO1 inhibits prostate cancer cell proliferation via suppressing E2F1 activated NPRL2 expression
Journal: Cell Biol Int | Authors: Yu Tang | Species: human | Application: WB,IF,ChIP - Thymidine Kinase 1 Drives Skin Cutaneous Melanoma Malignant Progression and Metabolic Reprogramming.
Journal: Front Oncol | Authors: Sipeng Zuo | Species: human | Application: WB - FGF14-AS2 accelerates tumorigenesis in glioma by forming a feedback loop with miR-320a/E2F1 axis.
Journal: J Cancer | Authors: Peng Zhang | Species: human | Application: WB - POLD2 is activated by E2F1 to promote triple-negative breast cancer proliferation
Journal: Front Oncol | Authors: Zhen Zhang | Species: human | Application: WB,ChIP - CDCA4/SERTAD1/E2F1 Facilitates Lung Adenocarcinoma Progression by Inhibiting PINK1/Parkin-Mediated Mitophagy.
Journal: IUBMB Life | Authors: Jianlong Tan | Species: human | Application: WB - GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells
Journal: J Immunol Res | Authors: Jing Ning | Species: human | Application: WB - E2F1-mediated GINS2 transcriptional activation promotes tumor progression through PI3K/AKT/mTOR pathway in hepatocellular carcinoma
Journal: Am J Cancer Res | Authors: Yao Zhang | Species: human | Application: WB - Long non-coding RNA SNHG1 activates glycolysis to promote hepatocellular cancer progression through the miR-326/PKM2 axis.
Journal: J Gene Med | Authors: Yue Wang | Species: human | Application: ChIP - Downregulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
Journal: J Gene Med | Authors: Jingjing Wu | Species: human | Application: WB - TRIM28 recruits E2F1 to regulate CBX8-mediated cell proliferation and tumor metastasis of ovarian cancer
Journal: Hum Cell | Authors: Fubin Zhang | Species: human | Application: WB,IHC - P129, a pyrazole ring-containing isolongifolanone-derivate: synthesis and investigation of anti-glioma action mechanism
Journal: Discov Oncol | Authors: Yining Jiang - Augmentation of the therapeutic efficacy of WEE1 kinase inhibitor AZD1775 by inhibiting the YAP-E2F1-DNA damage response pathway axis.
Journal: FEBS Open Bio | Authors: Yusuke Oku | Species: human | Application: WB - N-Acetyl-L-Cysteine Reduces Cervical Carcinogenesis by Promoting Apoptosis
Journal: Drugs R D | Authors: Wenping Guo | Species: human | Application: WB - siRNA Delivery for Control of Cyclin D1 and E2F1 Expression in Crohn's Disease.
Journal: Transl Med UniSa | Authors: Ilaria Russo | Species: human | Application: IHC - MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma
Journal: Bioengineered | Authors: Hui Liu | Species: human | Application: WB - U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis of leiomyosarcoma cells
Journal: Bioengineered | Authors: Yuguo Li | Species: human | Application: ChIP - Inhibition of Angiogenesis by MiR-524-5p through Suppression of AKT and ERK Activation by Targeting CXCR7 in Colon Cancer Cells
Journal: J Oncol | Authors: Xiang Li | Species: human | Application: WB - E2F-mediated POLA2 upregulation is correlated with macrophage infiltration and poor prognosis in hepatocellular carcinoma
Journal: Transl Cancer Res | Authors: Yao Teng | Species: human | Application: WB - HPV16 E7 Enhances Cell Stemness via RTKN2-Mediated Activation of the NF-κB Pathway in Cervical Cancer
Journal: Biochem Genet | Authors: Min Yang | Application: WB - Deletion of p16 accelerates fracture healing in geriatric mice.
Journal: Am J Transl Res | Authors: Qirui Ding | Species: human | Application: WB - Regular exercise suppresses steatosis-associated liver cancer development by degrading E2F1 and c-Myc via circadian gene upregulation
Journal: Genes Cells | Authors: Vu Thuong Huyen | Species: mouse | Application: WB - siRNA Delivery for Control of Cyclin D1 and E2F1 Expression in Crohn's Disease.
Journal: Transl Med UniSa | Authors: Ilaria Russo | Species: human | Application: IHC - DHCR24(+) tumor epithelial cells drive cisplatin resistance in bladder cancer by enhancing cholesterol metabolism to activate lipid raft-associated MAPK signaling.
Journal: Oncogene | Authors: Yuanqiao Zhao | Species: human | Application: WB
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