PE Anti-Mouse CD80 (16-10A1) PE-65076 proteintech
$107.00
In stock
SKU
PE-65076
| Catalog Number | PE-65076 |
| Synonyms | B7 1, B7.1, Cd28l, CD80 antigen, Ly 53 |
| Host | Armenian Hamster |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | IF, FC |
| Applications | FC |
| Host / Isotype | Armenian Hamster / IgG |
| Tested Applications — Positive FC detected in | mouse peritoneal macrophages |
| Positive FC detected in | mouse peritoneal macrophages |
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | mouse |
| Cited Reactivity | mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CHO cell line transfected with mouse B7 (CD80) Predict reactive species |
| Full Name | CD80 antigen |
| GenBank Accession Number | BC131959 |
| Gene Symbol | CD80 |
| Gene ID (NCBI) | 12519 |
| RRID | AB_2883872 |
| Conjugate | PE Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 496 nm, 565 nm / 578 nm |
| Excitation Laser | Blue Laser (488 nm), Green Laser (532 nm), Yellow-Green Laser (561 nm) |
| Purification Method | Affinity purification |
| UNIPROT ID | Q00609 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for PE CD80 antibody PE-65076 | Download protocol |
| mouse | FC Adv Sci (Weinh) A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma Authors - Zhuang Fan View Article |
| Citations | 18 |
| Isotype | IgG |
| Clonality | Monoclonal |
| Clone Number | 16-10A1 |
| Conjugation | PE |
CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215) Protocols Product Specific Protocols FC protocol for PE CD80 antibody PE-65076 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Synchronous Sterilization and Immunoreaction Termination for Corneal Transparency Protection in Treating Pseudomonas aeruginosa Induced Bacterial Keratitis
Journal: Adv Mater | Authors: Siyuan Qian | Species: mouse | Application: FC - Turning foes to friends: Advanced "in situ nanovaccine" with dual immunoregulation for enhanced immunotherapy of metastatic triple-negative breast cancer
Journal: Bioact Mater | Authors: Ze Wang | Species: mouse | Application: FC - Novel Pt(IV) complex OAP2 induces STING activation and pyroptosis via mitochondrial membrane remodeling for synergistic chemo-immunotherapy
Journal: Acta Pharm Sin B | Authors: Renming Fan | Species: mouse | Application: FC - [Not Available]
Journal: Small | Authors: Baochan Yang | Application: FC - Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells
Journal: Cell Rep | Authors: Yingqi Liu | Species: mouse | Application: FC - A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma
Journal: Adv Sci (Weinh) | Authors: Zhuang Fan | Species: mouse | Application: FC - A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma
Journal: Adv Sci (Weinh) | Authors: Zhuang Fan | Species: mouse | Application: FC - STAT3 interference-driven nanomodulators reverse lipid metabolism-associated chemoresistance and potentiate metalloimmunotherapy in breast cancer.
Journal: Cell Rep Med | Authors: Zifan Pei | Species: mouse | Application: FC - Lignin-assisted construction of sub-10 nm supramolecular self-assembly for photothermal immunotherapy and potentiating anti-PD-1 therapy against primary and distant breast tumors
Journal: Asian J Pharm Sci | Authors: Xudong Fan | Species: mouse | Application: FC - [Not Available]
Journal: Small | Authors: Baochan Yang | Application: FC - Wogonin modulates macrophage polarization and inflammatory signaling through the LSD1-p65 axis to alleviate osteoarthritis.
Journal: Phytomedicine | Authors: Zhe Cai | Species: mouse | Application: IF - Macro/Microgel-Encapsulated, Biofilm-Armored Living Probiotic Platform for Regenerating Bacteria-Infected Diabetic Wounds
Journal: Adv Healthc Mater | Authors: Huilong Xin | Species: mouse - Mn(2+)-loaded carboxymethyl chitosan nanoparticle as a multifunctional adjuvant to efficiently enhance the performance of inactivated pseudorabies virus vaccines.
Journal: Int J Biol Macromol | Authors: Niling Xie | Species: mouse | Application: FC - Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells
Journal: Cell Rep | Authors: Yingqi Liu | Species: mouse | Application: FC - An Electrochemical Biosensor for Detecting Calreticulin In Situ to Assess Immunogenic Cell Death in Tumor Cells.
Journal: Anal Chem | Authors: Zhenguo Zhang | Species: mouse | Application: FC - Noninvasive Transdermal Administration of mRNA Vaccines Encoding Multivalent Neoantigens Effectively Inhibits Melanoma Growth
Journal: ACS Biomater Sci Eng | Authors: Yuting Hou | Species: mouse | Application: FC - The Potential Role of Moringa oleifera Lam. Leaf Proteins in Moringa Allergy by Functionally Activating Murine Bone Marrow-Derived Dendritic Cells and Inducing Their Differentiation toward a Th2-Polarizing Phenotype
Journal: Nutrients | Authors: Chuyu Xi | Species: mouse | Application: FC - Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways
Journal: Int Immunopharmacol | Authors: Juan Yin | Application: FC
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