CoraLite® Plus 488 Anti-Mouse CD86 Rabbit Recombinant Antibody CL488-98025 proteintech
$137.00
In stock
SKU
CL488-98025
| Catalog Number | CL488-98025 |
| Synonyms | 230476B8, B7, B7 2, B7.2, B70 |
| Host | Rabbit |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | IF/ICC, FC |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive IF/ICC detected in | RAW 264.7 cells |
| Tested Applications — Positive FC detected in | LPS treated mouse splenocytes |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Positive IF/ICC detected in | RAW 264.7 cells |
| Positive FC detected in | LPS treated mouse splenocytes |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg0802 Product name: Recombinant Mouse CD86 protein (His Tag) Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 24-245 aa of NM_019388 Sequence: VSVETQAYFNGTAYLPCPFTKAQNISLSELVVFWQDQQKLVLYEHYLGTEKLDSVNAKYLGRTSFDRNNWTLRLHNVQIKDMGSYDCFIQKKPPTGSIILQQTLTELSVIANFSEPEIKLAQNVTGNSGINLTCTSKQGHPKPKKMYFLITNSTNEYGDNMQISQDNVTELFSISNSLSLSFPDGVWHMTVVCVLETESMKISSKPLNFTQEFPSPQTYWKE Predict reactive species |
| Full Name | CD86 antigen |
| Calculated Molecular Weight | 35 kDa |
| GenBank Accession Number | NM_019388 |
| Gene Symbol | Cd86 |
| Gene ID (NCBI) | 12524 |
| RRID | AB_3673370 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P42082-1 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 488 CD86 antibody CL488-98025 | Download protocol |
| IF protocol for CL Plus 488 CD86 antibody CL488-98025 | Download protocol |
| Citations | 1 |
| Dilutions | IF/ICC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 230476B8 |
| Conjugation | CoraLite® Plus 488 |
CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335) Protocols Product Specific Protocols FC protocol for CL Plus 488 CD86 antibody CL488-98025 Download protocol IF protocol for CL Plus 488 CD86 antibody CL488-98025 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Dynamic linking bone ECM-mimic hydrogel for anti-inflammatory therapy of cranial defect.
Journal: Colloids Surf B Biointerfaces | Authors: Tao Ge
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