CoraLite® Plus 750 Anti-Rat CD86 (24F) CL750-65224 proteintech
$137.00
In stock
SKU
CL750-65224
| Catalog Number | CL750-65224 |
| Synonyms | B7 2, Cd86, CD86 molecule |
| Host | Mouse |
| Reactivity | Rat |
| Reactivity | rat |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Mouse / IgG1, kappa |
| Tested Applications — Positive FC detected in | LPS-stimulated rat splenocytes |
| Positive FC detected in | LPS-stimulated rat splenocytes |
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | Rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | HTLV-1-transformed Lewis-S1 rat T cell line Predict reactive species |
| Full Name | CD86 molecule |
| Calculated Molecular Weight | 36 kDa |
| GenBank Accession Number | NM_020081 |
| Gene Symbol | Cd86 |
| Gene ID (NCBI) | 56822 |
| RRID | AB_3084871 |
| Conjugate | CoraLite® Plus 750 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 755 nm / 780 nm |
| Excitation Laser | Red Laser (633 nm) |
| Purification Method | Affinity purification |
| UNIPROT ID | O35531 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 750 CD86 antibody CL750-65224 | Download protocol |
| Citations | - |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Clone Number | 24F |
| Conjugation | CoraLite® Plus 750 |
CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Protocols Product Specific Protocols FC protocol for CL Plus 750 CD86 antibody CL750-65224 Download protocol Standard Protocols Click here to view our Standard Protocols
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