CoraLite®594 Anti-Rat CD8a (OX-8) Mouse IgG2a Recombinant Antibody CL594-65577 proteintech
$159.00
In stock
SKU
CL594-65577
| Catalog Number | CL594-65577 |
| Synonyms | CD8, CD8 antigen 32 kDa chain, CD8a molecule, OX-8, OX-8 membrane antigen |
| Host | Mouse |
| Reactivity | rat |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive FC detected in | rat splenocytes |
| Positive FC detected in | rat splenocytes |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | rat |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | High-molecular-weight rat thymocyte glycoproteins Predict reactive species |
| Full Name | CD8a molecule |
| GenBank Accession Number | BC088126 |
| Gene Symbol | Cd8a |
| Gene ID (NCBI) | 24930 |
| RRID | AB_3748109 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Excitation Laser | Yellow-Green Laser (561 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P07725 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL594 CD8a antibody CL594-65577 | Download protocol |
| Citations | - |
| Isotype | IgG2a |
| Clonality | Recombinant |
| Clone Number | OX-8 |
| Conjugation | CoraLite®594 |
CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells , on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084). Protocols Product Specific Protocols FC protocol for CL594 CD8a antibody CL594-65577 Download protocol Standard Protocols Click here to view our Standard Protocols
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