CoraLite® Plus 750 Anti-Mouse CD8a (53-6.7) CL750-65069 proteintech
$49.00
In stock
SKU
CL750-65069
| Catalog Number | CL750-65069 |
| Synonyms | CD8, 53-6.7, CD8 antigen, alpha chain, CD8α, Ly 2 |
| Host | Rat |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS, Azide |
| Applications | FC |
| Host / Isotype | Rat / IgG2a, kappa |
| Tested Applications — Positive FC detected in | mouse splenocytes |
| Positive FC detected in | mouse splenocytes |
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| Tested Reactivity | mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Spleen cells or thymocyte membranes Predict reactive species |
| Full Name | CD8 antigen, alpha chain |
| GenBank Accession Number | BC030679 |
| Gene Symbol | Cd8a |
| Gene ID (NCBI) | 12525 |
| RRID | AB_2935097 |
| Conjugate | CoraLite® Plus 750 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 755 nm / 780 nm |
| Excitation Laser | Red Laser (633 nm) |
| Purification Method | Affinity purification |
| UNIPROT ID | P01731 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 750 CD8a antibody CL750-65069 | Download protocol |
| Citations | 1 |
| Isotype | IgG2a, kappa |
| Clonality | Monoclonal |
| Clone Number | 53-6.7 |
| Conjugation | CoraLite® Plus 750 |
CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer, while CD8αα homodimers alone have been found on some gut intraepithelial T cells, on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084). Protocols Product Specific Protocols FC protocol for CL Plus 750 CD8a antibody CL750-65069 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Development of a Vaccine Candidate Based on Surface-Displayed Particles of Mycobacterium tuberculosis from the MTB39A Protein
Journal: Int J Mol Sci | Authors: Pu Wang | Application: FC
Product Documents
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
