Anti-Mouse CD8a Rat scFv Antibody SF65666-1-TR proteintech
$649.00
In stock
SKU
SF65666-1-TR
| Catalog Number | SF65666-1-TR |
| Synonyms | CD8, 53-6.7, CD8 antigen, alpha chain, CD8α, Ly 2 |
| Source | Anti-Mouse CD8a scFv from clone 53-6.7, consisting of VH-GGGGS linker-VL (N- to C-terminus), with a His-C tag at the C-terminus. |
| Host | Rat |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | HEPES, EDTA, CHAPS, Sucrose, Proclin300 |
| Applications | FC |
| Host / Isotype | mouse |
| Tested Applications — Positive FC detected in | mouse splenocytes |
| Positive FC detected in | mouse splenocytes |
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | mouse |
| Host / Type | Rat / scFv |
| Class | Recombinant |
| Type | Single-chain variable fragment antibody (scFv) |
| Immunogen | N/A Predict reactive species |
| Full Name | CD8 antigen, alpha chain |
| GenBank Accession Number | BC030679 |
| Gene Symbol | Cd8a |
| Gene ID (NCBI) | 12525 |
| RRID | AB_3750142 |
| Conjugate | Unconjugated |
| Purification Method | Affinity purification |
| Storage Buffer | 50mM HEPES, 150mM NaCl, 5mM EDTA, 0.1% CHAPS, 10% Sucrose and 0.1% Proclin300, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. 20ul sizes contain 0.1% BSA. |
| FC protocol for CD8a antibody SF65666-1-TR | Download protocol |
| Citations | - |
| Isotype | scFv |
| Clonality | Recombinant |
| Clone Number | 53-6.7 |
| Conjugation | Unconjugated |
CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells, on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084). Protocols Product Specific Protocols FC protocol for CD8a antibody SF65666-1-TR Download protocol Standard Protocols Click here to view our Standard Protocols
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