CDCA4 Polyclonal antibody 11625-1-AP proteintech
$149.00
In stock
SKU
11625-1-AP
| Catalog Number | 11625-1-AP |
| Synonyms | CDCA4, HEPP, SEI 3/HEPP |
| Host | Rabbit |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, IP, CoIP, ELISA |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HEK-293 cells, HeLa cells, MCF-7 cells, PC-3 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:3000 |
| Positive WB detected in | HEK-293 cells, HeLa cells, MCF-7 cells, PC-3 cells |
| Western Blot (WB) | WB : 1:500-1:3000 |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag2214 Product name: Recombinant human CDCA4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-241 aa of BC025263 Sequence: MFARGLKRKCVGHEEDVEGALAGLKTVSSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTQDGTWRTVAPQAAERAPLNRLVSTEILCRAAWGQEGAHPAPGLGDGHTQGPVSDLCPVTSAQAPRHLQSSAWEMDGPRENRGSFHKSLDQIFETLETKNPSCMEELFSDVDSPYYDLDTVLTGMMGGARPGPCEGLEGLAPATPGPSSSCKSDLGELDHVVEILVET Predict reactive species |
| Full Name | cell division cycle associated 4 |
| Calculated Molecular Weight | 241 aa, 26 kDa |
| Observed Molecular Weight | 33 kDa |
| GenBank Accession Number | BC025263 |
| Gene Symbol | CDCA4 |
| Gene ID (NCBI) | 55038 |
| RRID | AB_2260414 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9BXL8 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for CDCA4 antibody 11625-1-AP | Download protocol |
| mouse | WB Cancer Cell The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Authors - Ulf Klein KD Validated View Article |
| human | WB,IP Thorac Cancer CDCA4 interacts with IGF2BP1 to regulate lung adenocarcinoma proliferation via the PI3K/AKT pathway Authors - Sitong Feng KD Validated View Article |
| Citations | 14 |
| Dilutions | WB : 1:500-1:3000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
TRIP-Br proteins are a set of proteins with the potential to function in both transcriptional control and cell cycle regulation [PMID:18572021]. CECA4 is a member of TRIP-br family, based on its homologous sequence motifs including SERTA and a PHD-bromo-binding site which interacts with a series of bromodomain containing transcriptional cofactors[PMID:17141982]. When activated by E2F, CDCA4 consequently functions as a suppressor of E2F-responsive promoters to participate the regulation of cell proliferation through the E2F/pRb pathway [PMID:16098148]. Protocols Product Specific Protocols WB protocol for CDCA4 antibody 11625-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia.
Journal: Cancer Cell | Authors: Ulf Klein KD Validated | Species: mouse | Application: WB - Hepatocellular Carcinoma-propagating Cells are Detectable by Side Population Analysis and Possess an Expression Profile Reflective of a Primitive Origin.
Journal: Sci Rep | Authors: Honghai Xia | Species: human | Application: IF - CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy.
Journal: Cancer Cell Int | Authors: Chenxin Xu KD Validated | Species: human | Application: WB,CoIP - CDCA4 interacts with IGF2BP1 to regulate lung adenocarcinoma proliferation via the PI3K/AKT pathway
Journal: Thorac Cancer | Authors: Sitong Feng KD Validated | Species: human | Application: WB,IP - Roles of the CDCA gene family in breast carcinoma
Journal: Sci Prog | Authors: Wei Ding - Exosomal MicroRNA-424-5p From Polycystic Ovary Syndrome Follicular Fluid Attenuates Ovarian Inflammation via Targeting the Fibroblast Growth Factor 2/Fibroblast Growth Factor Receptor 1 Axis.
Journal: Cell Biochem Funct | Authors: Dong Yuan - CDCA4 as a novel molecular biomarker of poor prognosis in patients with lung adenocarcinoma
Journal: Front Oncol | Authors: Jianlong Tan | Species: human | Application: WB - CDCA4 promotes bladder cancer progression by JAK/STAT signaling pathway
Journal: J Cancer Res Clin Oncol | Authors: Peng Wan | Species: human | Application: WB - CDCA4/SERTAD1/E2F1 Facilitates Lung Adenocarcinoma Progression by Inhibiting PINK1/Parkin-Mediated Mitophagy.
Journal: IUBMB Life | Authors: Jianlong Tan | Species: human | Application: WB - IGF2BP2-induced circRNF20 facilitates breast cancer cell proliferation via the HuR/CDCA4 axis
Journal: Kaohsiung J Med Sci | Authors: Shu-Tao Wu | Species: human | Application: WB - ALKBH5 promotes the development of lung adenocarcinoma by regulating the polarization of M2 macrophages through CDCA4
Journal: Gene | Authors: Jianlong Tan | Species: human,mouse | Application: WB - Roles of the CDCA gene family in breast carcinoma
Journal: Sci Prog | Authors: Wei Ding - CDCA4 interacts with IGF2BP1 to regulate lung adenocarcinoma proliferation via the PI3K/AKT pathway
Journal: Thorac Cancer | Authors: Sitong Feng | Species: human | Application: WB,IP - Comprehensive molecular analyses and experimental validation of CDCAs with potential implications in kidney renal papillary cell carcinoma prognosis
Journal: Heliyon | Authors: Fuping Li | Species: human | Application: IHC
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