Cadherin-16 Polyclonal antibody 15107-1-AP proteintech
$149.00
In stock
SKU
15107-1-AP
| Catalog Number | 15107-1-AP |
| Synonyms | cadherin 16, KSP cadherin, Cadherin-16, CDH16, Kidney specific cadherin, Ksp cadherin |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, ELISA |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse kidney tissue, human kidney tissue, HEK-293 cells, rat kidney tissue |
| Tested Applications — Positive IHC detected in | human kidney tissue, human renal cell carcinoma tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:16000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | mouse kidney tissue, human kidney tissue, HEK-293 cells, rat kidney tissue |
| Positive IHC detected in | human kidney tissue, human renal cell carcinoma tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:2000-1:16000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag4343 Product name: Recombinant human CDH16 protein Source: e coli. -derived, T-HIS Tag: 6*His Domain: 20-350 aa of BC027912 Sequence: AQPAELSVEVPENYGGNFPLYLTKLPLPREGAEGQIVLSGDSGKATEGPFAMDPDSGFLLVTRALDREEQAEYQLQVTLEMQDGHVLWGPQPVLVHVKDENDQVPHFSQAIYRARLSRGTRPGIPFLFLEASDRDEPGTANSDLRFHILSQAPAQPSPDMFQLEPRLGALALSPKGSTSLDHALERTYQLLVQVKDMGDQASGHQATATVEVSIIESTWVSLEPIHLAENLKVLYPHHMAQVHWSGGDVHYHLESHPPGPFEVNAEGNLYVTRELDREAQAEYLLQVRAQNSHGEDYAAPLELHVLVMDENDNVPICPPRDPTVSIPELSP Predict reactive species |
| Full Name | cadherin 16, KSP-cadherin |
| Calculated Molecular Weight | 90 kDa |
| Observed Molecular Weight | 130 kDa |
| GenBank Accession Number | BC027912 |
| Gene Symbol | Cadherin-16 |
| Gene ID (NCBI) | 1014 |
| RRID | AB_10596931 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O75309 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for Cadherin-16 antibody 15107-1-AP | Download protocol |
| WB protocol for Cadherin-16 antibody 15107-1-AP | Download protocol |
| mouse | IF Cell Death Dis Blocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis. Authors - Huzi Xu View Article |
| human | WB Oncol Lett Cadherin-16 inhibits thyroid carcinoma cell proliferation and invasion. Authors - Xiaolin Yang View Article |
| Citations | 11 |
| Dilutions | WB : 1:2000-1:16000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Cadherin-16 (CDH16), also known as kidney-specific cadherin (Ksp-cadherin), is a tissue-specific member of the cadherin family of adhesion molecules (PMID: 7615566). It is a glycoprotein expressed by tubular epithelial cells in the kidney. Cadherin-16 expression is down-regulated in renal cell carcinoma, suggesting a role in tumor suppression (PMID: 15886705). Protocols Product Specific Protocols IHC protocol for Cadherin-16 antibody 15107-1-AP Download protocol WB protocol for Cadherin-16 antibody 15107-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Cytoplasmic HMGB1 induces renal tubular ferroptosis after ischemia/reperfusion
Journal: Int Immunopharmacol | Authors: Zhi Zhao | Species: mouse | Application: IF - Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.
Journal: Front Cell Dev Biol | Authors: Yanhong Zhang | Species: mouse | Application: WB,IF - Pax8 controls thyroid follicular polarity through Cadherin-16.
Journal: J Cell Sci | Authors: Petrina Koumarianou KD Validated | Species: mouse | Application: WB,IF - TMT-labeling Proteomics of Papillary Thyroid Carcinoma Reveal Invasive Biomarkers.
Journal: J Cancer | Authors: Jiaqi Dai | Species: human | Application: WB - Cadherin-16 inhibits thyroid carcinoma cell proliferation and invasion.
Journal: Oncol Lett | Authors: Xiaolin Yang | Species: human | Application: WB - Blocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis.
Journal: Cell Death Dis | Authors: Huzi Xu | Species: mouse | Application: IF
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