CHAC2 Polyclonal antibody 16304-1-AP proteintech
$149.00
In stock
SKU
16304-1-AP
| Catalog Number | 16304-1-AP |
| Synonyms | Glutathione-specific gamma-glutamylcyclotransferase 2, Gamma-GCG 2, EC:4.3.2.7, Cation transport regulator-like protein 2 |
| Host | Rabbit |
| Reactivity | human, mouse, rat and More (1) |
| Reactivity | human, mouse, rat, pig |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF/ICC, ELISA |
| Applications | WB, IF/ICC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | Jurkat cells, Raji cells |
| Tested Applications — Positive IF/ICC detected in | MCF-7 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:3000 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Positive WB detected in | Jurkat cells, Raji cells |
| Positive IF/ICC detected in | MCF-7 cells |
| Western Blot (WB) | WB : 1:1000-1:3000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat, pig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag9281 Product name: Recombinant human CHAC2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-184 aa of BC019239 Sequence: MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDPAGCVWGVAYRLPVGKEEEVKAYLDFREKGGYRTTTVIFYPKDPTTKPFSVLLYIGTCDNPDYLGPAPLEDIAEQIFNAAGPSGRNTEYLFELANSIRNLVPEEADEHLFALEKLVKERLEGKQNLNCI Predict reactive species |
| Full Name | ChaC, cation transport regulator homolog 2 (E. coli) |
| Calculated Molecular Weight | 184 aa, 21 kDa |
| Observed Molecular Weight | 21 kDa |
| GenBank Accession Number | BC019239 |
| Gene Symbol | CHAC2 |
| Gene ID (NCBI) | 494143 |
| RRID | AB_2229405 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WUX2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for CHAC2 antibody 16304-1-AP | Download protocol |
| WB protocol for CHAC2 antibody 16304-1-AP | Download protocol |
| pig | WB Cells Adh Promotes Actinobacillus pleuropneumoniae Survival in Porcine Alveolar Macrophages by Inhibiting CHAC2-Mediated Respiratory Burst and Inflammatory Cytokine Expression Authors - Junhui Zhu View Article |
| mouse | WB Environ Toxicol Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation. Authors - Xiaohan Zhai KD Validated View Article |
| human | WB Mol Neurobiol NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation Authors - Nan-Xiang Shen View Article |
| rat | WB,IHC,IF Int J Biol Sci Febuxostat therapy improved the outcomes of cardiorenal syndrome rodent through alleviating xanthine oxidase-induced oxidative stress and mitochondrial dysfunction Authors - Chih-Chao Yang View Article |
| Citations | 8 |
| Dilutions | WB : 1:1000-1:3000 IF/ICC : 1:200-1:800 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
CHAC2 is a gamma-glutamyl cyclotransferase that catalyzes the conversion of glutathione to 5-oxoproline and cysteinylglycine. CHAC2 is involved in continuous, basal turnover of cytosolic glutathione(PMID: 27913623). Protocols Product Specific Protocols IF protocol for CHAC2 antibody 16304-1-AP Download protocol WB protocol for CHAC2 antibody 16304-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Adh Promotes Actinobacillus pleuropneumoniae Survival in Porcine Alveolar Macrophages by Inhibiting CHAC2-Mediated Respiratory Burst and Inflammatory Cytokine Expression
Journal: Cells | Authors: Junhui Zhu | Species: pig | Application: WB - Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.
Journal: Environ Toxicol | Authors: Xiaohan Zhai KD Validated | Species: mouse | Application: WB - Hypoxia-driven phase separation of the PABP1/eIF4B complex forms stress granules and activates ChaC2 translation to promote polyunsaturated lipids-supported peritoneal metastasis in gastric cancer.
Journal: Cancer Lett | Authors: Zaihuan Lin | Species: human | Application: WB,IHC,IF - SGLT2 inhibitor downregulated oxidative stress via activating AMPK pathway for cardiorenal (CR) protection in CR syndrome rodent fed with high protein diet
Journal: J Mol Histol | Authors: Chih-Chao Yang | Species: rat | Application: IHC,IF - NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation
Journal: Mol Neurobiol | Authors: Nan-Xiang Shen | Species: human | Application: WB - Febuxostat therapy improved the outcomes of cardiorenal syndrome rodent through alleviating xanthine oxidase-induced oxidative stress and mitochondrial dysfunction
Journal: Int J Biol Sci | Authors: Chih-Chao Yang | Species: rat | Application: WB,IHC,IF
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