BAD Monoclonal antibody 67830-1-Ig proteintech
$149.00
In stock
SKU
67830-1-Ig
| Catalog Number | 67830-1-Ig |
| Synonyms | 4B12G2, BBC2, BBC6, Bcl2-associated agonist of cell death, Bcl-2-binding component 6 |
| Host | Mouse |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF/ICC, ELISA |
| Applications | WB, IF/ICC, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | LNCaP cells, RAW 264.7 cells, HeLa cells, HEK-293 cells, Jurkat cells, Raji cells, THP-1 cells, HSC-T6 cells |
| Tested Applications — Positive IF/ICC detected in | HeLa cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:6000 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:400-1:1600 |
| Positive WB detected in | LNCaP cells, RAW 264.7 cells, HeLa cells, HEK-293 cells, Jurkat cells, Raji cells, THP-1 cells, HSC-T6 cells |
| Positive IF/ICC detected in | HeLa cells |
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:400-1:1600 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | BCL2-associated agonist of cell death |
| Calculated Molecular Weight | 18 kDa |
| Observed Molecular Weight | 18-25 kDa |
| GenBank Accession Number | BC001901 |
| Gene Symbol | BAD |
| Gene ID (NCBI) | 572 |
| RRID | AB_2918592 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | Q92934 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for BAD antibody 67830-1-Ig | Download protocol |
| WB protocol for BAD antibody 67830-1-Ig | Download protocol |
| human | WB Acta Biochim Biophys Sin (Shanghai) Triptonide facilitates autophagy-mediated apoptosis in esophageal squamous cell carcinoma by targeting the AMPK-mTOR-ULK1 axis. Authors - Jiujun Ju View Article |
| rat | WB Oxid Med Cell Longev Curcumin Inhibits Hyperandrogen-Induced IRE1α-XBP1 Pathway Activation by Activating the PI3K/AKT Signaling in Ovarian Granulosa Cells of PCOS Model Rats Authors - Yaling Zhang View Article |
| Citations | 14 |
| Dilutions | WB : 1:1000-1:6000 IF/ICC : 1:400-1:1600 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 4B12G2 |
| Conjugation | Unconjugated |
BAD, also named as BBC6 and BCL2L8, promotes cell death. It is successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. BAD can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. It appears to act as a link between growth factor receptor signaling and the apoptotic pathways. Protocols Product Specific Protocols IF protocol for BAD antibody 67830-1-Ig Download protocol WB protocol for BAD antibody 67830-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Mitochondrial tRNAGlu 14693A>G Mutation, an "Enhancer" to the Phenotypic Expression of Leber's Hereditary Optic Neuropathy
Journal: Adv Sci (Weinh) | Authors: Lihao Jin | Species: human | Application: WB - Curcumin Inhibits Hyperandrogen-Induced IRE1α-XBP1 Pathway Activation by Activating the PI3K/AKT Signaling in Ovarian Granulosa Cells of PCOS Model Rats
Journal: Oxid Med Cell Longev | Authors: Yaling Zhang | Species: rat | Application: WB - Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
Journal: FASEB J | Authors: Xueying Chen | Species: human | Application: WB - RGS2 attenuates alveolar macrophage damage by inhibiting the Gq/11-Ca2+ pathway during cowshed PM2.5 exposure, and aberrant RGS2 expression is associated with TLR2/4 activation
Journal: Toxicol Appl Pharmacol | Authors: Zhenhua Ma | Species: human | Application: WB - ND‑09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR‑ABL signaling
Journal: Oncol Rep | Authors: Yan-Hong Liu | Species: human | Application: WB - Triptonide facilitates autophagy-mediated apoptosis in esophageal squamous cell carcinoma by targeting the AMPK-mTOR-ULK1 axis.
Journal: Acta Biochim Biophys Sin (Shanghai) | Authors: Jiujun Ju | Species: human | Application: WB - Protective role of RGS2 in PM2.5-induced ovarian injury in rats: Modulation of Gq/11 signaling to maintain granulosa cell [Ca2 + ]i stability
Journal: Ecotoxicol Environ Saf | Authors: Zhenhua Ma | Species: rat | Application: WB - Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB
Journal: Int Immunopharmacol | Authors: Yun Liu | Species: human | Application: WB - ND‑09 inhibits chronic myeloid leukemia K562 cell growth by regulating BCR‑ABL signaling
Journal: Oncol Rep | Authors: Yan-Hong Liu | Species: human | Application: WB - Triptonide facilitates autophagy-mediated apoptosis in esophageal squamous cell carcinoma by targeting the AMPK-mTOR-ULK1 axis.
Journal: Acta Biochim Biophys Sin (Shanghai) | Authors: Jiujun Ju | Species: human | Application: WB - Glucose-dependent insulinotropic polypeptide modifies adipose plasticity and promotes beige adipogenesis of human omental adipose-derived stem cells.
Journal: FASEB J | Authors: Xueying Chen | Species: human | Application: WB - Ginsenoside Re Regulates Oxidative Stress through the PI3K/Akt/Nrf2 Signaling Pathway in Mice with Scopolamine-Induced Memory Impairments
Journal: Curr Issues Mol Biol | Authors: Xin Li | Species: mouse | Application: WB - Tripartite motif-containing 67 promotes progression of hepatocellular carcinoma by regulating MAPK signaling pathway.
Journal: Hepatobiliary Pancreat Dis Int | Authors: Zhuang Zhou | Species: human | Application: WB,IHC - RGS2 attenuates alveolar macrophage damage by inhibiting the Gq/11-Ca2+ pathway during cowshed PM2.5 exposure, and aberrant RGS2 expression is associated with TLR2/4 activation
Journal: Toxicol Appl Pharmacol | Authors: Zhenhua Ma | Species: human | Application: WB
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
