CPT2 Monoclonal antibody 68815-3-Ig proteintech
$149.00
In stock
SKU
68815-3-Ig
| Catalog Number | 68815-3-Ig |
| Synonyms | Carnitine O-palmitoyltransferase 2, mitochondrial, carnitine palmitoyltransferase 2, CPT II, CPTASE, EC:2.3.1.21 |
| Host | Mouse |
| Reactivity | human, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | HeLa cells, LNCaP cells, rat liver tissue, HepG2 cells, Jurkat cells, K-562 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Positive WB detected in | HeLa cells, LNCaP cells, rat liver tissue, HepG2 cells, Jurkat cells, K-562 cells |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Tested Reactivity | human, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag24833 Product name: Recombinant human CPT2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 32-178 aa of BC002445 Sequence: GQYLQRSIVPTMHYQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYILGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHL Predict reactive species |
| Full Name | carnitine palmitoyltransferase 2 |
| Calculated Molecular Weight | 74 kDa |
| Observed Molecular Weight | 65-70 kDa |
| GenBank Accession Number | BC002445 |
| Gene Symbol | CPT2 |
| Gene ID (NCBI) | 1376 |
| RRID | AB_3743315 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | P23786 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for CPT2 antibody 68815-3-Ig | Download protocol |
| Citations | - |
| Dilutions | WB : 1:5000-1:50000 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 3F11C10 |
| Conjugation | Unconjugated |
Carnitine palmitoyltransferase-1 and -2 (CPT1 and CPT2) are two genetically distinct mitochondrial membrane bound enzymes and play critical role in the regulation of FAO in normal cells. CPT2 is an ubiquitous protein and locates in the inner membrane of mitochondrial (PMID: 29437870). CPT2 is frequently down-regulated in primary ovarian serous carcinomas, which is significantly correlated with poor survival of ovarian cancer patients (PMID: 33486313). Down-regulation of CPT2 was a major cause of acylcarnitine accumulation and a common feature in mouse models of obesity- and NASH-driven HCC and human SH-HCC (PMID: 29872321). Protocols Product Specific Protocols WB protocol for CPT2 antibody 68815-3-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
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