C-Reactive Protein/CRP Polyclonal antibody 24175-1-AP proteintech
$149.00
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SKU
24175-1-AP
| Catalog Number | 24175-1-AP |
| Synonyms | CRP, PTX1, C-reactive protein(1-205), C-Reactive Protein, C reactive protein |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, ELISA |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | rat plasma, serum from mouse injected with bacteria, human plasma |
| Tested Applications — Positive IHC detected in | human liver tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:1000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | rat plasma, serum from mouse injected with bacteria, human plasma |
| Positive IHC detected in | human liver tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag21466 Product name: Recombinant human CRP protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 19-224 aa of BC125135 Sequence: QTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP Predict reactive species |
| Full Name | C-reactive protein, pentraxin-related |
| Calculated Molecular Weight | 224 aa, 25 kDa |
| Observed Molecular Weight | 25-28 kDa |
| GenBank Accession Number | BC125135 |
| Gene Symbol | CRP |
| Gene ID (NCBI) | 1401 |
| RRID | AB_2879447 |
| Conjugate | Unconjugated |
| Purification Method | Antigen Affinity purified |
| UNIPROT ID | P02741 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for C-Reactive Protein/CRP antibody 24175-1-AP | Download protocol |
| WB protocol for C-Reactive Protein/CRP antibody 24175-1-AP | Download protocol |
| human, mouse | WB J Proteome Res Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients. Authors - Shizhen Qin View Article |
| human | WB Biomed Mater Reversing cytotoxicity of uric acid by supramolecular encapsulation with acyclic cucurbit[n]uril. Authors - Lingguang Kong View Article |
| mouse | IF J Orthop Translat An aptamer specifically targeting mCRP ameliorates experimental arthritis. Authors - Zhuqian Wang View Article |
| Kamal (Verified Customer) (01-22-2026) | Liver lysates were subjected to SDS PAGE followed by western blot with 24175-1-AP (C-Reactive Protein/CRP antibody) at dilution of 1:2000 incubated overnight. Applications: Western Blot Primary Antibody Dilution: 1:2000 Cell Tissue Type: Mouse Liver tissue |
| Citations | 11 |
| Dilutions | WB : 1:500-1:1000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation. Protocols Product Specific Protocols IHC protocol for C-Reactive Protein/CRP antibody 24175-1-AP Download protocol WB protocol for C-Reactive Protein/CRP antibody 24175-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Journal: J Proteome Res | Authors: Shizhen Qin | Species: human, mouse | Application: WB - Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease.
Journal: J Proteome Res | Authors: Yong Zhou | Species: human | Application: WB - Reversing cytotoxicity of uric acid by supramolecular encapsulation with acyclic cucurbit[n]uril.
Journal: Biomed Mater | Authors: Lingguang Kong | Species: human | Application: WB - In vitro and in vivo study of andrographolide nanoparticles for the treatment of Mycoplasma pneumoniae pneumonia
Journal: Biochem Biophys Res Commun | Authors: Liling Wang | Species: mouse | Application: IHC - TLR4 gene in the regulation of periodontitis and its molecular mechanism.
Journal: Exp Ther Med | Authors: Weijuan Qi - An aptamer specifically targeting mCRP ameliorates experimental arthritis.
Journal: J Orthop Translat | Authors: Zhuqian Wang | Species: mouse | Application: IF - Reversing cytotoxicity of uric acid by supramolecular encapsulation with acyclic cucurbit[n]uril.
Journal: Biomed Mater | Authors: Lingguang Kong | Species: human | Application: WB - Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease.
Journal: J Proteome Res | Authors: Yong Zhou | Species: human | Application: WB - Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Journal: J Proteome Res | Authors: Shizhen Qin | Species: human, mouse | Application: WB - In vitro and in vivo study of andrographolide nanoparticles for the treatment of Mycoplasma pneumoniae pneumonia
Journal: Biochem Biophys Res Commun | Authors: Liling Wang | Species: mouse | Application: IHC - TLR4 gene in the regulation of periodontitis and its molecular mechanism.
Journal: Exp Ther Med | Authors: Weijuan Qi
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