CXCR4/CD184 Polyclonal antibody 33828-1-AP proteintech
$149.00
In stock
SKU
33828-1-AP
| Catalog Number | 33828-1-AP |
| Synonyms | CXCR4, CD184, C-X-C chemokine receptor type 4, CXC R4, CXCR 4 |
| Host | Rabbit |
| Reactivity | human, mouse, rat and More (1) |
| Reactivity | human, mouse, rat, rabbit |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IF, ELISA |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse brain tissue, mouse spleen tissue, rat brain tissue, rat spleen tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Positive WB detected in | mouse brain tissue, mouse spleen tissue, rat brain tissue, rat spleen tissue |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag40645 Product name: Recombinant human CXCR4/CD184 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 303-352 aa of BC020968 Sequence: AFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS Predict reactive species |
| Full Name | chemokine (C-X-C motif) receptor 4 |
| Calculated Molecular Weight | 352 aa, 40 kDa |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | BC020968 |
| Gene Symbol | CXCR4 |
| Gene ID (NCBI) | 7852 |
| RRID | AB_3743084 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | P61073 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for CXCR4/CD184 antibody 33828-1-AP | Download protocol |
| rabbit | IF,WB Anim Biosci Transcriptomic analysis identifies CXCL12 as a novel candidate gene for litter size in rabbits. Authors - Zhiyuan Bao View Article |
| Citations | 3 |
| Dilutions | WB : 1:500-1:2000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
C-X-C chemokine receptor type 4 (CXCR4) is a widely expressed G protein-coupled seven-transmembrane receptor. CXCL12/SDF-1 is the biological ligand for CXCR4. The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription (PMID: 20484021). CXCR4 also functions as a coreceptor for HIV-1 entry (PMID: 9427609). CXCR4 has a calculated molecular weight of 40 kDa. In addition to the predicted species of 45-47 kDa for glycosylated CXCR4 monomers, due to ubiquitination, dimeration, and different degrees of glycosylation, additional species can also exist and have been reported in some research, including 67 kDa (PMID: 23917520), 55, 67, 87 kDa (PMID: 20028517), 80 kDa (PMID: 10506573), 47, 50, 62, and 98 kDa (PMID: 16204649). Protocols Product Specific Protocols WB protocol for CXCR4/CD184 antibody 33828-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Relationship between Th1/Th2 balance and medical abortion outcomes in early medical abortion patients.
Journal: Clin Immunol | Authors: Ting Feng - Transcriptomic analysis identifies CXCL12 as a novel candidate gene for litter size in rabbits.
Journal: Anim Biosci | Authors: Zhiyuan Bao | Species: rabbit | Application: IF,WB - CXCR4 targeting by TPCA‑1 attenuates neuroinflammation in intracerebral hemorrhage through inhibiting NF‑κB and AP‑1 activation.
Journal: Int J Biochem Cell Biol | Authors: Na Wang
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