Cyclin A2 Polyclonal antibody 18202-1-AP proteintech
$149.00
In stock
SKU
18202-1-AP
| Catalog Number | 18202-1-AP |
| Synonyms | CCNA2, CCN1, CCNA, Cyclin A, Cyclin-A |
| Host | Rabbit |
| Reactivity | human, mouse and More (5) |
| Reactivity | human, mouse, rat, pig, rabbit, monkey, sheep |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, FC (Intra), IP, CoIP, ELISA |
| Applications | WB, FC (Intra), IP, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HL-60 cells, K-562 cells, U-937 cells, HeLa cells, NIH/3T3 cells, MCF-7 cells |
| Tested Applications — Positive IP detected in | HeLa cells, HL-60 cells |
| Tested Applications — Positive IHC detected in | human tonsillitis tissue, human breast cancer tissue, human colon cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Tested Applications — Positive IF/ICC detected in | HepG2 cells, MCF-7 cells |
| Tested Applications — Positive FC (Intra) detected in | HeLa cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:500-1:2000 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Positive WB detected in | HL-60 cells, K-562 cells, U-937 cells, HeLa cells, NIH/3T3 cells, MCF-7 cells |
| Positive IP detected in | HeLa cells, HL-60 cells |
| Positive IHC detected in | human tonsillitis tissue, human breast cancer tissue, human colon cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | HepG2 cells, MCF-7 cells |
| Positive FC (Intra) detected in | HeLa cells |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunohistochemistry (IHC) | IHC : 1:500-1:2000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse, rat, pig, rabbit, monkey, sheep |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag12765 Product name: Recombinant human Cyclin A2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-432 aa of BC104783 Sequence: MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL Predict reactive species |
| Full Name | cyclin A2 |
| Calculated Molecular Weight | 432 aa, 49 kDa |
| Observed Molecular Weight | 48-52 kDa |
| GenBank Accession Number | BC104783 |
| Gene Symbol | Cyclin A2 |
| Gene ID (NCBI) | 890 |
| RRID | AB_10597084 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P20248 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for Cyclin A2 antibody 18202-1-AP | Download protocol |
| IHC protocol for Cyclin A2 antibody 18202-1-AP | Download protocol |
| IP protocol for Cyclin A2 antibody 18202-1-AP | Download protocol |
| WB protocol for Cyclin A2 antibody 18202-1-AP | Download protocol |
| rat | WB Cell Metab Sphingolipid metabolism controls mammalian heart regeneration Authors - Xiaoqian Ji View Article |
| mouse | Acta Pharm Sin B The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway. Authors - Weimin Yu View Article |
| human | WB Sci Adv The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis Authors - Zhenlong Yu View Article |
| Citations | 247 |
| Dilutions | WB : 1:5000-1:50000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB IHC : 1:500-1:2000 IF/ICC : 1:200-1:800 FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Cyclin A2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. Cyclin A2 binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Cyclin A2 could be phosphorylated during the G2/M. Protocols Product Specific Protocols IF protocol for Cyclin A2 antibody 18202-1-AP Download protocol IHC protocol for Cyclin A2 antibody 18202-1-AP Download protocol IP protocol for Cyclin A2 antibody 18202-1-AP Download protocol WB protocol for Cyclin A2 antibody 18202-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Sphingolipid metabolism controls mammalian heart regeneration
Journal: Cell Metab | Authors: Xiaoqian Ji | Species: rat | Application: WB - LIFR regulates cholesterol-driven bidirectional hepatocyte-neutrophil cross-talk to promote liver regeneration
Journal: Nat Metab | Authors: Yalan Deng | Species: mouse | Application: WB - A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
Journal: Mol Cell | Authors: Kaiwen Bao - CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA.
Journal: Mol Cancer | Authors: Bing Yao | Species: human | Application: WB - The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
Journal: Acta Pharm Sin B | Authors: Weimin Yu | Species: mouse - The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis
Journal: Sci Adv | Authors: Zhenlong Yu | Species: human | Application: WB - Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells.
Journal: Nat Commun | Authors: Jiawei Zhang | Species: human | Application: WB - Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling
Journal: Nat Commun | Authors: Ying Cheng | Species: human | Application: WB - CFAP100 couples microtubule glutamylation to spindle pole integrity in keratinocytes to promote epidermal development.
Journal: Nat Commun | Authors: Shuang Sun | Species: human | Application: WB - Restoration of RBM22 overcomes the transcriptional and epigenetic barriers of cardiomyocyte proliferation for heart regeneration
Journal: Nat Commun | Authors: Xuewen Duan | Species: human | Application: WB - Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice
Journal: Nat Commun | Authors: Yanhao Chen | Species: mouse | Application: WB - ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury
Journal: Nat Commun | Authors: Yankun Zhang | Species: mouse | Application: WB - ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis.
Journal: Cell Discov | Authors: Wenjun Kuang | Species: human | Application: WB - A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
Journal: Mol Cell | Authors: Kaiwen Bao - (131)I/MTX-loaded engineered outer membrane vesicles for sequentially coordinated radio-metabolic-immunotherapy of glioma.
Journal: J Nanobiotechnology | Authors: Maolin Liang | Species: mouse | Application: WB - Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.
Journal: J Nanobiotechnology | Authors: Xiuying Li | Species: human | Application: WB - MK8722 initiates early-stage autophagy while inhibiting late-stage autophagy via FASN-dependent reprogramming of lipid metabolism
Journal: Theranostics | Authors: Luhui Wang | Species: human | Application: WB - Beyond ribosomal function: RPS6 deficiency suppresses cholangiocarcinoma cell growth by disrupting alternative splicing
Journal: Acta Pharm Sin B | Authors: Wenkang Fu | Species: human | Application: WB - The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway.
Journal: Acta Pharm Sin B | Authors: Weimin Yu | Species: mouse - EVI5 is an oncogene that regulates the proliferation and metastasis of NSCLC cells.
Journal: J Exp Clin Cancer Res | Authors: Tingting Cai | Species: human | Application: WB - The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis
Journal: Sci Adv | Authors: Zhenlong Yu | Species: human | Application: WB - Epithelial cells-enriched lncRNA SNHG8 regulates chromatin condensation by binding to Histone H1s
Journal: Cell Death Differ | Authors: Ping He | Species: human | Application: WB - Inactivation of TACC2 epigenetically represses CDKN1A and confers sensitivity to CDK inhibitors
Journal: Med | Authors: Zhi-Rui Lin | Species: human | Application: WB - AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.
Journal: Cell Death Dis | Authors: Minhao Chen | Species: rat | Application: WB - HDAC7/c-Myc signaling pathway promotes the proliferation and metastasis of choroidal melanoma cells
Journal: Cell Death Dis | Authors: Yimeng Zhang | Species: mouse,human | Application: WB - CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy
Journal: Cell Death Dis | Authors: Xinyue Gao | Species: human | Application: WB - Targeting TRAF6/IRF3 axis to inhibit NF-κB-p65 nuclear translocation enhances the chemosensitivity of 5-FU and reverses the proliferation of gastric cancer
Journal: Cell Death Dis | Authors: Shitong Chen | Species: human | Application: WB - Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage
Journal: Cell Death Dis | Authors: Martin D Burkhalter | Species: human | Application: WB - The miR-6240 target gene Igf2bp3 promotes myoblast fusion by enhancing myomaker mRNA stability
Journal: Cell Mol Biol Lett | Authors: Yuxin Huang | Species: mouse | Application: WB - PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway
Journal: Cell Death Dis | Authors: Ming Cheng | Species: human | Application: WB - AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.
Journal: Cell Death Dis | Authors: Minhao Chen | Species: rat | Application: WB - TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis
Journal: Cell Death Dis | Authors: Yuzhen Wang | Species: human | Application: WB - Translating m6A-Glycolysis Discovery into Therapy: GOQD-Based Multifunctional Bioactive Scaffolds Rejuvenates Bone Repair in Senescence.
Journal: Small | Authors: Zengguang Wang | Species: rat | Application: WB - RRM2 is a potential prognostic biomarker with functional significance in glioma.
Journal: Int J Biol Sci | Authors: Hongzhi Sun | Species: human | Application: WB - Ebastine exerts antitumor activity and induces autophagy by activating AMPK/ULK1 signaling in an IPMK-dependent manner in osteosarcoma
Journal: Int J Biol Sci | Authors: Zhen Pan | Species: human | Application: WB - ESRG is critical to maintain the cell survival and self-renewal/pluripotency of hPSCs by collaborating with MCM2 to suppress p53 pathway
Journal: Int J Biol Sci | Authors: Shasha Li | Species: human | Application: WB - Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
Journal: Cell Commun Signal | Authors: Ruosi Yao | Species: human | Application: WB - Isotoosendanin exerts anti-tumor effects in NSCLC by enhancing the stability of SHP-2 and inhibiting the JAK/STAT3 pathway
Journal: Phytomedicine | Authors: Chenying Shu | Species: human | Application: WB - The anti-non-small cell lung cancer effect of Diosbulbin B: Targeting YY1 induced cell cycle arrest and apoptosis
Journal: Phytomedicine | Authors: Jin-Quan Zhao | Species: mouse,human | Application: WB - Taraxasterol regulates p53 transcriptional activity to inhibit pancreatic cancer by inducing MDM2 ubiquitination degradation
Journal: Phytomedicine | Authors: Anna Han | Species: human | Application: WB - Sesamol serves as a p53 stabilizer to relieve rheumatoid arthritis progression and inhibits the growth of synovial organoids
Journal: Phytomedicine | Authors: Xian Lin | Species: human | Application: WB - Xanthotoxol suppresses non-small cell lung cancer progression and might improve patients' prognosis
Journal: Phytomedicine | Authors: Xian Lin | Application: WB - Dendrobin A inhibits gastric cancer: Mechanistic insights supported by integrated evidence
Journal: Phytomedicine | Authors: Yonghao Fan | Application: WB - The anti-non-small cell lung cancer effect of Diosbulbin B: Targeting YY1 induced cell cycle arrest and apoptosis
Journal: Phytomedicine | Authors: Jin-Quan Zhao | Species: mouse,human | Application: WB - Constructing a 3D co-culture in vitro synovial tissue model for rheumatoid arthritis research
Journal: Mater Today Bio | Authors: Xiaocheng Wang | Species: human | Application: WB - SREBP1 knockdown triggers ferroptosis by suppressing the Nrf2-XCT/GPX4 axis in ovarian cancer.
Journal: Cell Death Discov | Authors: Rui Nie | Species: human | Application: WB - Rheum emodin inhibits enterovirus 71 viral replication and affects the host cell cycle environment.
Journal: Acta Pharmacol Sin | Authors: Ting Zhong | Species: monkey | Application: WB - Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation.
Journal: Cell Death Discov | Authors: Zhenzhen Sun | Species: mouse | Application: WB - Muscle RING finger-1 facilitates skeletal muscle regeneration via regulating myoblast proliferation and differentiation.
Journal: J Transl Med | Authors: Mengge Yang | Species: human | Application: WB - Triclabendazole inhibits PKM2 nuclear localization and glycolysis by enhancing HDAC6-mediated deacetylation in lung cancer
Journal: J Transl Med | Authors: Liang Yan | Application: WB - Alpha-ketoglutarate restores oral epithelial homeostasis via FOXM1-mediated cell cycle regulation.
Journal: Sci China Life Sci | Authors: Yuan Wang | Species: human | Application: WB - Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer
Journal: Oncogene | Authors: Yuquan Bai | Species: human | Application: WB - Targeting NUF2 suppresses gastric cancer progression through G2/M phase arrest and apoptosis induction
Journal: Chin Med J (Engl) | Authors: Bo Long | Species: human | Application: WB - Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.
Journal: Chin Med J (Engl) | Authors: Ze-Yuan Yu | Species: human | Application: WB - Therapeutic Targeting of RNA Polymerase I With the Small-Molecule CX-5461 for Prevention of Arterial Injury-Induced Neointimal Hyperplasia.
Journal: Arterioscler Thromb Vasc Biol | Authors: Qing Ye - Photothermal exposure of polydopamine-coated branched Au-Ag nanoparticles induces cell cycle arrest, apoptosis, and autophagy in human bladder cancer cells.
Journal: Int J Nanomedicine | Authors: Xiaoming Zhao | Species: human | Application: WB - Fibroblast-Specific Depletion of Human Antigen R Alleviates Myocardial Fibrosis Induced by Cardiac Stress
Journal: JACC Basic Transl Sci | Authors: Mallikarjun Patil | Species: human | Application: WB - Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma
Journal: Phytother Res | Authors: Ronghui Fan | Species: human | Application: WB - Gambogenic acid induces apoptosis and autophagy through ROS-mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells
Journal: Phytother Res | Authors: Jianjian Wu | Species: human | Application: WB - Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3‐mediated N6‐methyladenosine modification of ICAM2 mRNA in fibroblast‐like synoviocytes
Journal: Clin Transl Med | Authors: Jian Chen | Species: human | Application: WB - Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3‐mediated N6‐methyladenosine modification of ICAM2 mRNA in fibroblast‐like synoviocytes
Journal: Clin Transl Med | Authors: Jian Chen | Species: human | Application: WB - Copper-Induced Cuproptosis and Immunogenic Cell Death Synergize with Radiotherapy and PD-1 Blockade in Osteosarcoma
Journal: ACS Appl Mater Interfaces | Authors: Jia Yao | Species: mouse - Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation.
Journal: Stem Cell Res Ther | Authors: Ruhui Tian | Species: human | Application: WB - Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
Journal: Cell Rep | Authors: Pingping Wang | Species: mouse,human | Application: WB - Proanthocyanidin oligomers extract from hawthorn mediates cell cycle arrest, apoptosis, and lysosome vacuolation on HCT116 cells
Journal: Curr Res Food Sci | Authors: Ya-Sai Sun | Species: human | Application: WB - DSCC1 restrains 53BP1/RIF1 signaling at DNA double-strand breaks to promote homologous recombination repair
Journal: Cell Rep | Authors: Jiaxin Tian | Species: human | Application: WB - IMPDH2 dephosphorylation under FGFR signaling promotes S-phase progression and tumor growth
Journal: Cell Rep | Authors: Bei Zhou | Species: human | Application: WB - DSCC1 restrains 53BP1/RIF1 signaling at DNA double-strand breaks to promote homologous recombination repair
Journal: Cell Rep | Authors: Jiaxin Tian | Species: human | Application: WB - Quantitative differences between cyclin-dependent kinases underlie the unique functions of CDK1 in human cells.
Journal: Cell Rep | Authors: Ho Wai Lau | Species: human | Application: WB - Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma.
Journal: Cell Rep | Authors: Yun Yang | Species: human | Application: WB - Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Journal: Cell Prolif | Authors: Qin Tang | Species: human | Application: WB - Blockade of JAK2 protects mice against hypoxia-induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation.
Journal: Cell Prolif | Authors: Lei Zhang | Species: mouse | Application: WB - MicroRNA-191 promotes hepatocellular carcinoma cell proliferation by has_circ_0000204/miR-191/KLF6 axis.
Journal: Cell Prolif | Authors: Fang Tian | Species: human | Application: WB - Phenolic zingerone nanoparticles impede cell cycle progression to compete against human urothelial carcinoma.
Journal: Biomed Pharmacother | Authors: Mei-Lang Kung | Species: human | Application: WB - Dendrobium nobile active ingredient Dendrobin A against hepatocellular carcinoma via inhibiting nuclear factor kappa-B signaling
Journal: Biomed Pharmacother | Authors: Yaping Yu | Species: human | Application: WB - Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.
Journal: Chin Med | Authors: Hui Liu | Species: human | Application: WB - Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV
Journal: Environ Pollut | Authors: Zhiwen Zheng | Species: human | Application: WB - REC8-Cohesin Preferentially Localizes to Promoters of Genes that are Regulated by Transcription Suppressor BEND2 During Early Meiosis.
Journal: Genomics Proteomics Bioinformatics | Authors: Dan Xie | Species: mouse | Application: WB - The ALDH Family Contributes to Immunocyte Infiltration, Proliferation and Epithelial-Mesenchymal Transformation in Glioma.
Journal: Front Immunol | Authors: Zeyu Wang | Species: human | Application: WB - PTBP3 regulates proliferation of lung squamous cell carcinoma cells via CDC25A-mediated cell cycle progression.
Journal: Cancer Cell Int | Authors: Yingji Chen | Species: human | Application: WB - Exploring the carcinogenic potential of bisphenol A in lung adenocarcinoma: molecular mechanisms, key gene insights, and immune microenvironment impacts.
Journal: Front Immunol | Authors: Haizhu Chen | Species: human | Application: WB - Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
Journal: Cancer Cell Int | Authors: Jiayu Ma | Species: human | Application: WB - Narciclasine inhibits phospholipase A2 and regulates phospholipid metabolism to ameliorate psoriasis-like dermatitis
Journal: Front Immunol | Authors: Yi Kong | Species: human | Application: WB - WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC
Journal: Lipids Health Dis | Authors: Rui Wang | Species: human | Application: WB - Combining transcriptomics and network pharmacology to reveal the mechanism of Zuojin capsule improving spasmolytic polypeptide-expressing metaplasia
Journal: J Ethnopharmacol | Authors: Mengyuan Xiong | Species: mouse,human | Application: WB - Synthesis, molecular modeling, biological and pharmacokinetic evaluation of hydroxy pyrimidinones and pyrimidinediones as novel LDHA inhibitors.
Journal: Eur J Med Chem | Authors: Horrick Sharma | Species: human | Application: WB - Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity.
Journal: Ecotoxicol Environ Saf | Authors: Liling Su | Species: human | Application: WB - Targeting EGFR with sanguinarine chloride: a novel approach to bladder cancer therapy.
Journal: Biochem Pharmacol | Authors: Hui Cheng | Species: human | Application: WB - Modulation of cell cycle increases CRISPR-mediated homology-directed DNA repair
Journal: Cell Biosci | Authors: Guoling Li | Species: human | Application: WB - GALNT7 promotes the malignant progression of gastrointestinal stromal tumors by regulating KIT O-GalNAc glycosylation.
Journal: Precis Clin Med | Authors: Jiahao Liu | Species: human | Application: WB - GALNT7 promotes the malignant progression of gastrointestinal stromal tumors by regulating KIT O-GalNAc glycosylation.
Journal: Precis Clin Med | Authors: Jiahao Liu | Species: human | Application: WB - Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress.
Journal: Oncotarget | Authors: Yafei Dai | Species: human | Application: WB - Proteomics, Transcriptomics, and Phosphoproteomics Reveal the Mechanism of Talaroconvolutin-A Suppressing Bladder Cancer via Blocking Cell Cycle and Triggering Ferroptosis
Journal: Mol Cell Proteomics | Authors: Yong Xia | Species: human | Application: WB - An oral phenylacrylic acid derivative suppressed hepatic stellate cell activation and ameliorated liver fibrosis by blocking TGF-β1 signalling
Journal: Liver Int | Authors: Taixiong Xue | Species: human | Application: WB - m6Am methyltransferase PCIF1 negatively regulates ciliation by inhibiting BICD2 expression
Journal: J Cell Biol | Authors: Shanshan Xie | Species: human | Application: WB - GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner
Journal: EMBO Rep | Authors: Munan Shi | Species: human | Application: WB - GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner
Journal: EMBO Rep | Authors: Munan Shi | Species: human | Application: WB - lncRNA SNHG4 modulates colorectal cancer cell cycle and cell proliferation through regulating miR-590-3p/CDK1 axis.
Journal: Aging (Albany NY) | Authors: Zhongyi Zhou | Species: human | Application: WB - A novel PVA/QCS/AgNP hydrogel with antibacterial and healing-promoting efficacy for preventing postoperative pancreatic fistula in rats.
Journal: Colloids Surf B Biointerfaces | Authors: Yuan Zhou | Species: rat | Application: WB - IGF2BP3 recruits NUDT21 to regulate SPTBN1 alternative polyadenylation and drive ovarian cancer progression
Journal: Commun Biol | Authors: Xin Luo | Species: human | Application: WB - A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.
Journal: Commun Biol | Authors: Masashi Watanabe | Species: human | Application: WB - Semaphorin 4C promotes macrophage recruitment and angiogenesis in breast cancer.
Journal: Mol Cancer Res | Authors: Jie Yang | Species: human - Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling.
Journal: Clin Epigenetics | Authors: Yingge Liu | Species: human | Application: WB - CT2-3 induces cell cycle arrest and apoptosis in rheumatoid arthritis fibroblast-like synoviocytes through regulating PI3K/AKT pathway
Journal: Eur J Pharmacol | Authors: Jian Chen | Species: human | Application: WB - The NF-κB/miR-488/ERBB2 axis modulates pancreatic cancer cell malignancy and tumor growth through cell cycle signaling.
Journal: Cancer Biol Ther | Authors: Duo Han | Species: mouse,human | Application: WB - Arecoline hydrobromide suppresses PI3K/AKT pathway in rheumatoid arthritis synovial fibroblasts and relieves collagen-induced arthritis in mice
Journal: Int Immunopharmacol | Authors: Jiaxin He | Species: human | Application: WB - 8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells
Journal: Int J Mol Sci | Authors: Dianbao Zhang | Species: human - Simvastatin Downregulates Cofilin and Stathmin to Inhibit Skeletal Muscle Cells Migration.
Journal: Int J Mol Sci | Authors: Li-Ping Lin | Species: rat | Application: WB - Z-Ligustilide Combined with Cisplatin Reduces PLPP1-Mediated Phospholipid Synthesis to Impair Cisplatin Resistance in Lung Cancer
Journal: Int J Mol Sci | Authors: Pengyu Geng | Species: human | Application: WB - Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma
Journal: Cell Oncol (Dordr) | Authors: Ashley M Fuller | Species: mouse,human | Application: WB - Moringa oleifera Lam. Isothiocyanate Quinazolinone Derivatives Inhibit U251 Glioma Cell Proliferation through Cell Cycle Regulation and Apoptosis Induction
Journal: Int J Mol Sci | Authors: Jing Xie | Species: human | Application: WB - Arecoline hydrobromide suppresses PI3K/AKT pathway in rheumatoid arthritis synovial fibroblasts and relieves collagen-induced arthritis in mice
Journal: Int Immunopharmacol | Authors: Jiaxin He | Species: human | Application: WB - Simvastatin Downregulates Cofilin and Stathmin to Inhibit Skeletal Muscle Cells Migration.
Journal: Int J Mol Sci | Authors: Li-Ping Lin | Species: rat | Application: WB - Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway.
Journal: Int J Mol Sci | Authors: Jiahui Yuan | Species: human | Application: WB - Simvastatin Downregulates Cofilin and Stathmin to Inhibit Skeletal Muscle Cells Migration.
Journal: Int J Mol Sci | Authors: Li-Ping Lin | Species: rat | Application: WB - The Phytochemical Rhein Mediates M6A-Independent Suppression of Adipocyte Differentiation.
Journal: Front Nutr | Authors: Linyuan Huang | Species: mouse | Application: WB - c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy
Journal: Biol Direct | Authors: Yunyun Wang | Application: WB - CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland
Journal: Invest Ophthalmol Vis Sci | Authors: Linyan Ma | Species: mouse | Application: WB - Vitamin D3 promotes gastric cancer cell autophagy by mediating p53/AMPK/mTOR signaling
Journal: Front Pharmacol | Authors: Yanan Wang | Species: human | Application: WB - The type I ribosome-inactivating protein α-MMC induced significant apoptosis of lung cancer A549 and 95-D cells by activating the caspase cascade through TNF signaling pathway
Journal: Front Pharmacol | Authors: Di Yang | Species: human | Application: WB - Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells
Journal: J Periodontal Res | Authors: Zixuan Li | Species: human | Application: WB - Identification and verification of hub genes associated with the progression of non-small cell lung cancer by integrated analysis
Journal: Front Pharmacol | Authors: Xie Mengyan | Species: human | Application: WB - Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro.
Journal: Biol Res | Authors: Zhihua Gan | Species: human | Application: WB - Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1.
Journal: Front Pharmacol | Authors: Minhui Yang | Species: human | Application: WB - Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Journal: Front Pharmacol | Authors: Dong Wang | Species: human | Application: WB - ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts
Journal: J Periodontal Res | Authors: Yaoyao Zhu | Species: human | Application: WB - ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts
Journal: J Periodontal Res | Authors: Yaoyao Zhu | Species: human | Application: WB - A novel non-nad-based PARP1 inhibitor, Japoflavone B, triggered Caspase-3/GSDME-mediated pyroptosis through ROS/p38/p53 pathway in NSCLC
Journal: Chem Biol Interact | Authors: Haoqiang Wan - A natural flavagline derivative A2073 inhibits the proliferation of erythroleukemia cells by targeting the MAPK, PI3K, NF-κB, and cell cycle pathways
Journal: Bioorg Chem | Authors: Man Zhou | Species: human | Application: WB - Inhibition of DNA Topoisomerase Ι by Flavonoids and Polyacetylenes Isolated from Bidens pilosa L
Journal: Molecules | Authors: Guiyuan Zeng | Species: human | Application: WB - Total saponins from Rhizoma Panacis Majoris inhibit proliferation, induce cell cycle arrest and apoptosis and influence MAPK signalling pathways on the colorectal cancer cell.
Journal: Mol Med Rep | Authors: Lu Chang | Species: human | Application: WB - Identification of Immune-Related Lactylation Genes in Rheumatoid Arthritis With Atherosclerosis: A Comprehensive Analysis Using Bulk and Single-Cell RNA Sequencing Data.
Journal: Mediators Inflamm | Authors: Jiaqi Hu | Species: mouse | Application: WB - SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells
Journal: J Mol Cell Cardiol | Authors: Langtao Wang | Species: mouse | Application: WB - Low C6orf141 Expression is Significantly Associated with a Poor Prognosis in Patients with Oral Cancer.
Journal: Sci Rep | Authors: Cheng-Mei Yang | Species: human | Application: WB - SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells.
Journal: Stem Cell Rev Rep | Authors: Xiaomin Liao | Species: mouse | Application: WB - PAK5 drives vascular remodeling in hypoxic pulmonary hypertension via Drp1-dependent mitochondrial midzone division.
Journal: Sci Rep | Authors: Junming Zhang | Species: rat | Application: WB - Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone metastatic cancer.
Journal: Sci Rep | Authors: Wei-Liang Ye | Species: mouse | Application: WB - Identification of IQGAP3 prognostic potential and involvement in immune cell infiltration in LUAD
Journal: Eur J Med Res | Authors: Mingduan Chen | Species: human | Application: WB - Identification of IQGAP3 prognostic potential and involvement in immune cell infiltration in LUAD
Journal: Eur J Med Res | Authors: Mingduan Chen | Species: human | Application: WB - Antitumour effects of artesunate via cell cycle checkpoint controls in human oesophageal squamous carcinoma cells
Journal: Eur J Med Res | Authors: Linlin Mao | Species: human | Application: WB - MKRN2-Mediated Degradation of IGF2BP3 Suppresses MYC and Enhances CDK4/6 Inhibitor Sensitivity in Bladder Cancer.
Journal: Cancers (Basel) | Authors: Qi Pan - Metformin Treatment Suppresses Melanoma Cell Growth and Motility Through Modulation of microRNA Expression.
Journal: Cancers (Basel) | Authors: Hui-Wen Tseng | Species: human | Application: WB - Pseudolaric acid B inhibits neuroglioma cell proliferation through DNA damage response.
Journal: Oncol Rep | Authors: Fengmei Song - G protein subunit α q regulates gastric cancer growth via the p53/p21 and MEK/ERK pathways.
Journal: Oncol Rep | Authors: Yizhuo Wang | Species: human | Application: WB - Pseudolaric acid B inhibits neuroglioma cell proliferation through DNA damage response.
Journal: Oncol Rep | Authors: Fengmei Song - TROAP regulates prostate cancer progression via the WNT3/survivin signalling pathways.
Journal: Oncol Rep | Authors: Jianqing Ye | Species: human | Application: WB - miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Journal: Cell Signal | Authors: Xiang Xiong | Species: human | Application: WB - A novel biphenyl urea compound, TPD7, stimulates apoptosis through modulating Fas signaling and Bcl-2 family proteins in cervical cancer.
Journal: Oncol Rep | Authors: Yingzhuan Zhan | Application: WB - c-myc-mediated upregulation of NAT10 facilitates tumor development via cell cycle regulation in non-small cell lung cancer.
Journal: Med Oncol | Authors: Zimu Wang | Species: human | Application: WB - Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells.
Journal: Oncol Rep | Authors: Liangliang Jin | Species: human | Application: WB - ACSS2 is required for colorectal cancer progression and a druggable target for colorectal cancer treatment.
Journal: iScience | Authors: Lei Wang | Species: mouse,human | Application: WB - A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network.
Journal: iScience | Authors: Di Chen | Application: WB,CoIP - Epithelial cell expansion drives cyst progression in genetic models of autosomal recessive polycystic kidney disease.
Journal: iScience | Authors: Shuncheng Liu | Species: rat,mouse | Application: WB,IF - β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight.
Journal: Biomedicines | Authors: Agustín Hidalgo-Gutiérrez | Species: mouse | Application: WB - Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells.
Journal: Acta Biochim Biophys Sin (Shanghai) | Authors: Zishu Wang | Species: human | Application: WB - Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis
Journal: iScience | Authors: Xiaoting Wang | Species: mouse,human | Application: WB - Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Journal: FASEB J | Authors: Jiangfeng Li | Species: human | Application: WB - Thymidine Kinase 1 Mediates the Synergistic Antitumor Activity of Ubenimex and Celecoxib via Regulation of Cell Cycle in Colorectal Cancer
Journal: J Pharmacol Exp Ther | Authors: Aimin Wang | Species: mouse,human | Application: WB - CgTNF-2 promotes the proliferation of haemocytes by regulating the expressions of CgRunx and cell cycle related genes in the Pacific oyster Crassostrea gigas
Journal: Fish Shellfish Immunol | Authors: Wei Wu | Species: mouse | Application: WB - USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1.
Journal: J Virol | Authors: Edmund Osei Kuffour | Species: human | Application: WB - Polychlorinated biphenyl quinone metabolite promotes p53-dependent DNA damage checkpoint activation, S-phase cycle arrest and extrinsic apoptosis in human liver hepatocellular carcinoma HepG2 Cells.
Journal: Chem Res Toxicol | Authors: Xiufang Song | Species: human | Application: WB - Rosuvastatin Ameliorates the Initiation and Progression of Lung Adenocarcinoma via Facilitating PLK1 Inhibition.
Journal: Front Biosci (Landmark Ed) | Authors: Jie Yin | Species: human | Application: WB - Porcine Circovirus 2 Activates the PERK-Reactive Oxygen Species Axis To Induce p53 Phosphorylation with Subsequent Cell Cycle Arrest at S Phase in Favor of Its Replication
Journal: J Virol | Authors: Zhuofan Deng | Species: pig | Application: WB - IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Journal: J Cell Physiol | Authors: Zhecun Wang | Species: human | Application: WB - The potential mechanism of Neu5Gc inducing colorectal cancer based on network pharmacology and experimental validation
Journal: Naunyn Schmiedebergs Arch Pharmacol | Authors: Li-Chao Zhang | Species: human | Application: WB - Revealing the active ingredients and mechanisms of Xiatianwu against hepatocellular carcinoma: a study based on network pharmacology and bioinformatics
Journal: Naunyn Schmiedebergs Arch Pharmacol | Authors: Hui Wang | Species: mouse,human | Application: WB - VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2.
Journal: Cell Cycle | Authors: Liangyu Zhao | Species: mouse | Application: WB - A Novel Gene Pair CSTF2/DPE2A Impacts Prognosis and Cell Cycle of Hepatocellular Carcinoma
Journal: J Hepatocell Carcinoma | Authors: Yangjin Huang | Species: human | Application: WB - Lnc-PKNOX1-1 inhibits tumor progression in cutaneous malignant melanoma by regulating NF-κB/IL-8 axis
Journal: Carcinogenesis | Authors: Anlan Hong | Species: human | Application: WB - Identification of a Proteomic Signature of Senescence in Primary Human Mammary Epithelial Cells
Journal: J Proteome Res | Authors: Alireza Delfarah | Species: human | Application: WB - Pracinostat inhibits the nefarious biological behavior of pancreatic cancer by targeting the miR-381-3p/MDM2 axis to activate the p53 signaling pathway.
Journal: Pathol Res Pract | Authors: Dongyun Cun | Species: human | Application: WB - A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway
Journal: Epigenetics | Authors: Cheng Zhu | Species: human | Application: WB - Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC
Journal: J Nat Prod | Authors: Hongyan Lin | Species: human | Application: WB - Mometasone furoate inhibits tumor progression and promotes apoptosis through activation of the AMPK/mTOR signaling pathway in osteosarcoma
Journal: J Bone Oncol | Authors: Zhaohui Li | Species: human | Application: WB - EGFR tyrosine kinase inhibitor ZZC4 overcomes acquired resistance to gefitinib
Journal: Toxicol Appl Pharmacol | Authors: Mawusse K I Attiogbe | Species: human | Application: WB - Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway
Journal: Mol Carcinog | Authors: Shengbang Wang | Species: human | Application: WB - PTENp1, a natural sponge of miR-21, mediates PTEN expression to inhibit the proliferation of oral squamous cell carcinoma.
Journal: Mol Carcinog | Authors: Ling Gao | Species: human | Application: WB - Fungal metabolite altersolanol a exhibits potent cytotoxicity against human placental trophoblasts in vitro via mitochondria-mediated apoptosis
Journal: Mycotoxin Res | Authors: Ting Gu | Species: human | Application: WB - LMNB1 deletion in ovarian cancer inhibits the proliferation and metastasis of tumor cells through PI3K/Akt pathway
Journal: Exp Cell Res | Authors: Jian Dong | Species: mouse,human | Application: WB - Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1
Journal: Exp Cell Res | Authors: Zijun Guo | Species: human | Application: WB - MAPRE3 as an epigenetic target of EZH2 restricts ovarian cancer proliferation in vitro and in vivo
Journal: Exp Cell Res | Authors: Yun Zhang | Species: human | Application: WB - PTENp1, a natural sponge of miR-21, mediates PTEN expression to inhibit the proliferation of oral squamous cell carcinoma.
Journal: Mol Carcinog | Authors: Ling Gao | Species: human | Application: WB - Liensinine inhibits progression of intrahepatic cholangiocarcinoma by regulating TGF-β1 /P-smad3 signaling through HIF-1a
Journal: Mol Carcinog | Authors: Xuewen Zhu | Species: human | Application: WB - Proline-rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway
Journal: Mol Carcinog | Authors: Shengbang Wang | Species: human | Application: WB - Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1
Journal: Exp Cell Res | Authors: Zijun Guo | Species: human | Application: WB - Lin28 promotes dental pulp cell proliferation via upregulation of cyclin-dependent proteins and interaction with let-7a/IGF2BP2 pathways.
Journal: Biomed Pharmacother | Authors: Yan Liu | Species: human | Application: WB - Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle.
Journal: J Cancer | Authors: Rui Yang | Species: human | Application: WB - CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.
Journal: Front Oncol | Authors: Hongyi Li | Species: mouse,human | Application: WB - RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway
Journal: Front Oncol | Authors: Jinhai Li | Species: human | Application: WB - Potential Role of SWI/SNF Complex Subunit Actin-Like Protein 6A in Cervical Cancer.
Journal: Front Oncol | Authors: Qingying Wang | Species: human | Application: WB - Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Journal: Front Oncol | Authors: Xinbing Zhu | Species: human | Application: WB - Identification of MAD2L1 as a novel biomarker for hepatoblastoma through bioinformatics and machine learning approaches
Journal: Front Oncol | Authors: Ying He | Species: human | Application: WB - CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.
Journal: Front Oncol | Authors: Hongyi Li | Species: mouse,human | Application: WB - Reduced FANCE Confers Genomic Instability and Malignant Behavior by Regulating Cell Cycle Progression in Endometrial Cancer
Journal: J Cancer | Authors: Chunying Zheng | Species: human | Application: WB - Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Journal: Front Oncol | Authors: Xinbing Zhu | Species: human | Application: WB - Potential Role of SWI/SNF Complex Subunit Actin-Like Protein 6A in Cervical Cancer.
Journal: Front Oncol | Authors: Qingying Wang | Species: human | Application: WB - Developing a prognostic stratification model based on glutathione metabolism in thyroid cancer and validating RRM2's tumor-promoting role
Journal: Front Oncol | Authors: Wei Ao | Species: mouse,human | Application: WB - Radix Glycyrrhizae Preparata Induces Cell Cycle Arrest and Induced Caspase-Dependent Apoptosis in Glioblastoma Multiforme
Journal: Neurol Int | Authors: Tsung-Ying Lin | Species: human | Application: WB - RTA404, an Activator of Nrf2, Activates the Checkpoint Kinases and Induces Apoptosis through Intrinsic Apoptotic Pathway in Malignant Glioma.
Journal: J Clin Med | Authors: Tai-Hsin Tsai | Species: human | Application: WB - Targeting RACGAP1 suppresses growth hormone pituitary adenoma growth
Journal: Endocrine | Authors: Feifan Sun | Species: rat | Application: WB - Nuclear receptor co-activator 4 interacts with RUVBL1/2 to maintain genome integrity through double-strand break repair.
Journal: DNA Repair (Amst) | Authors: Yingying Chen | Species: human | Application: WB - Attenuation of pro-tumorigenic senescent secretory phenotype by StN, a novel derivative of stevioside, potentiates its inhibitory activity on hepatocellular carcinoma
Journal: Food Chem Toxicol | Authors: Yanxia Guo | Species: human | Application: WB - SARS-CoV-2 nucleocapsid protein delays cell cycle in S-phase
Journal: Int J Med Microbiol | Authors: Jinming Liu | Application: WB - GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells
Journal: J Immunol Res | Authors: Jing Ning | Species: human | Application: WB - A natural halogenated fluoride adenosine analog 5'-fluorodeoxy adenosine induced anticolon cancer activity in vivo and in vitro.
Journal: Environ Toxicol | Authors: Long Ma | Species: mouse | Application: WB - Kruppel like factor 12 gene regulates ovarian granulosa cells proliferation and apoptosis via the PI3K/Akt signaling pathway.
Journal: BMC Vet Res | Authors: Jiawei Cai | Species: rabbit | Application: WB - KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Journal: Front Genet | Authors: Huiling Liao | Species: human | Application: WB - Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of sp1 to inhibit lung cancer growth.
Journal: Mol Pharmacol | Authors: Hsu Tsung-I TI | Species: human | Application: WB - miR-133 could affect proliferation and apoptosis of ovine granulosa cells by regulating the expression of B4GALNT2.
Journal: Theriogenology | Authors: Yangyu Bai | Species: sheep | Application: WB - Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Journal: Biomed Res Int | Authors: Yuanshen Mao | Species: human | Application: WB - Cytotoxic Chaetoglobosins From a Soil-derived Chaetomium sp.
Journal: Chem Biodivers | Authors: Jie Xu | Species: human | Application: WB - High Expression of PTGR1 Promotes NSCLC Cell Growth via Positive Regulation of Cyclin-Dependent Protein Kinase Complex.
Journal: Biomed Res Int | Authors: Xianping Huang | Species: human | Application: WB - Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.
Journal: Biomed Res Int | Authors: Yuanshen Mao | Species: human | Application: WB - A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement.
Journal: Mol Biosyst | Authors: Langdong Chen - Mitophagy is responsible to ionizing radiation but plays a very limited role in the radiosensitivity of adenocarcinoma cells.
Journal: Hum Cell | Authors: Chen Yan | Species: human | Application: WB - Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Journal: PLoS One | Authors: Ying Zhao | Species: human | Application: WB - Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo.
Journal: PLoS One | Authors: Ying Zhao | Species: human | Application: WB - PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways.
Journal: Biomed Pharmacother | Authors: Bing-Ya Yang | Species: human | Application: WB - Overexpression of myosin VI regulates gastric cancer cell progression.
Journal: Gene | Authors: Zishu Wang | Species: human | Application: WB - STAT3-mediated activation of mitochondrial pathway contributes to antitumor effect of dihydrotanshinone I in esophageal squamous cell carcinoma cells.
Journal: World J Gastrointest Oncol | Authors: Ming-Ming Qi | Species: human | Application: WB - The Role of the Y Box Binding Protein 1 C-Terminal Domain in Vascular Endothelial Cell Proliferation, Apoptosis, and Angiogenesis.
Journal: DNA Cell Biol | Authors: Wei Wang | Species: human | Application: WB - CDCA4 interacts with IGF2BP1 to regulate lung adenocarcinoma proliferation via the PI3K/AKT pathway
Journal: Thorac Cancer | Authors: Sitong Feng | Species: human | Application: WB - LOC100506691 Is an Oncogenic Long Noncoding RNA that Promotes Growth and Motility of Lung Cancer Cells
Journal: Cancer Genomics Proteomics | Authors: Yu-Hsuan Chen | Species: human | Application: WB - MCTS1 promotes laryngeal squamous cell carcinoma cell growth via enhancing LARP7 stability.
Journal: Clin Exp Pharmacol Physiol | Authors: Mengsheng Yang | Species: human | Application: WB - Prepubertal exposure to copper oxide nanoparticles induces Leydig cell injury with steroidogenesis disorders in mouse testes
Journal: Biochem Biophys Res Commun | Authors: Xiangqin Zheng | Species: human | Application: WB - Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway.
Journal: Cancer Chemother Pharmacol | Authors: Peng Xu | Species: human | Application: WB - Deficiency of VCP-Interacting Membrane Selenoprotein (VIMP) Leads to G1 Cell Cycle Arrest and Cell Death in MIN6 Insulinoma Cells.
Journal: Cell Physiol Biochem | Authors: Lili Men | Species: human | Application: WB - NCAPH regulates gastric cancer progression through DNA damage response
Journal: Neoplasma | Authors: Yan Wang - Lobaplatin for the treatment of SK-MES-1 lung squamous cell line in vitro and in vivo.
Journal: Onco Targets Ther | Authors: Hongming Zhang | Species: human | Application: WB - The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines.
Journal: Onco Targets Ther | Authors: Yameng Wei | Species: human | Application: WB - Modulation of cyclins and p53 in mesangial cell proliferation and apoptosis during Habu nephritis.
Journal: Clin Exp Nephrol | Authors: Yang Lu | Species: mouse | Application: WB - Long noncoding RNA LOC441461 drives cancer growth and is associated with poor clinical outcomes.
Journal: Tzu Chi Med J | Authors: Ching-Feng Cheng | Species: human | Application: WB - Spindle and kinetochore-associated complex 3 promotes cell growth via the PI3K/AKT/GSK3β and PI3K/AKT/FOXO1 pathways and is a potential prognostic biomarker for oral squamous cell carcinoma
Journal: Oral Surg Oral Med Oral Pathol Oral Radiol | Authors: Haoyue Xu | Species: human | Application: WB - Parasympathetic-macrophages-ductal epithelial cells axis promotes female rat submandibular gland regeneration after excretory duct ligation/deligation
Journal: Arch Oral Biol | Authors: Bin Wang | Species: rat | Application: WB - Identification of a transcription factor‑cyclin family genes network in lung adenocarcinoma through bioinformatics analysis and validation through RT‑qPCR
Journal: Exp Ther Med | Authors: Xiaodong Yang | Species: human | Application: WB - UHRF1 knockdown attenuates cell growth, migration, and invasion in cutaneous squamous cell carcinoma.
Journal: Cancer Invest | Authors: Qingyan Li | Species: human | Application: WB - RANBP9 suppresses tumor proliferation in colorectal cancer.
Journal: Oncol Lett | Authors: Chunzhi Qin | Species: human | Application: WB - OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression
Journal: In Vitro Cell Dev Biol Anim | Authors: Yuqiang Yin | Species: human | Application: WB - Effects of 4-vinylcyclohexene diepoxide on the cell cycle, apoptosis, and steroid hormone secretion of goat ovarian granulosa cells.
Journal: In Vitro Cell Dev Biol Anim | Authors: Yuyang Miao | Application: WB - Effects of dietary folic acid supplementation on lactation performance and mammary epithelial cell development of dairy cows and its regulatory mechanism
Journal: Anim Biotechnol | Authors: Jing Zhang | Application: WB - Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells.
Journal: Am J Transl Res | Authors: Zhen-Hua Chen | Species: human | Application: WB - Copper Chaperone Atox1 Protected the Cochlea From Cisplatin by Regulating the Copper Transport Family and Cell Cycle
Journal: Int J Toxicol | Authors: Xubo Chen | Species: mouse | Application: WB - The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression.
Journal: Elife | Authors: Tonya Kueck | Species: human | Application: WB - Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
Journal: Asian Pac J Cancer Prev | Authors: Ousman Tamgue | Species: human | Application: WB - LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration
Journal: bioRxiv | Authors: Yalan Deng | Species: mouse | Application: WB - Gut Microbiota-derived Acetate Safeguards the Colonic Epithelial Acetyl-CoA Reserve to Avert Colonic Senescence.
Journal: bioRxiv | Authors: Jie Du | Species: mouse | Application: WB - Gut Microbiota-derived Acetate Safeguards the Colonic Epithelial Acetyl-CoA Reserve to Avert Colonic Senescence.
Journal: bioRxiv | Authors: Jie Du | Species: mouse | Application: WB - Stevioside promotes hepatocyte proliferation via YAP signaling in cholestatic disease.
Journal: Acta Pharmacol Sin | Authors: Wei Jiang - Combined inhibition of BETs and HDACs as a potential epigenetics-based therapy for malignant rhabdoid tumor.
Journal: Cell Death Dis | Authors: Lingyan Zhu
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