STAR Monoclonal antibody 67130-1-Ig proteintech
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67130-1-Ig
| Catalog Number | 67130-1-Ig |
| Synonyms | 1G6E6, STARD1, START domain-containing protein 1 |
| Host | Mouse |
| Reactivity | human, mouse, rat, pig |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF-P, IF-Fro, ELISA |
| Applications | WB, IF-P, IF-Fro, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | pig adrenal gland tissue, human adrenal gland tissue, human testis tissue, K-562 cells, rat adrenal gland tissue, rat testis tissue, THP-1 cells, Mo7e cells |
| Tested Applications — Positive IF-P detected in | mouse testis tissue |
| Tested Applications — Positive IF-Fro detected in | mouse testis tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Recommended Dilutions — Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| Recommended Dilutions — Immunofluorescence (IF)-FRO | IF-FRO : 1:200-1:800 |
| Positive WB detected in | pig adrenal gland tissue, human adrenal gland tissue, human testis tissue, K-562 cells, rat adrenal gland tissue, rat testis tissue, THP-1 cells, Mo7e cells |
| Positive IF-P detected in | mouse testis tissue |
| Positive IF-Fro detected in | mouse testis tissue |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| Immunofluorescence (IF)-FRO | IF-FRO : 1:200-1:800 |
| Tested Reactivity | human, mouse, rat, pig |
| Cited Reactivity | mouse, rat, pig |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag28698 Product name: Recombinant human STAR protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-285 aa of BC010550 Sequence: MLLATFKLCAGSSYRHMRNMKGLRQQAVMAISQELNRRALGGPTPSTWINQVRRRSSLLGSRLEETLYSDQELAYLQQGEEAMQKALGILSNQEGWKKESQQDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKIGKDTFITHELAAEAAGNLVGPRDFVSVRCAKRRGSTCVLAGMATDFGNMPEQKGVIRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKSIINQVLSQTQVDFANHLRKRLESHPASEARC Predict reactive species |
| Full Name | steroidogenic acute regulatory protein |
| Calculated Molecular Weight | 285 aa, 32 kDa |
| Observed Molecular Weight | 28-32 kDa |
| GenBank Accession Number | BC010550 |
| Gene Symbol | STAR |
| Gene ID (NCBI) | 6770 |
| RRID | AB_2882429 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | P49675 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for STAR antibody 67130-1-Ig | Download protocol |
| WB protocol for STAR antibody 67130-1-Ig | Download protocol |
| mouse | WB Int Immunopharmacol Melatonin orchestrates cAMP-PKA signaling to alleviate zearalenone-impaired the estradiol synthesis in mammal ovary. Authors - Qiao Li View Article |
| Citations | 14 |
| Dilutions | WB : 1:5000-1:50000 IF-P : 1:200-1:800 IF-FRO : 1:200-1:800 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1G6E6 |
| Conjugation | Unconjugated |
Steroidogenic acute regulatory protein (StAR) is a key player in acute regulation of hormone-induced steroidogenesis, by facilitating cholesterol transport from cellular stores to inner mitochondria membrane where the cholesterol was conversed to pregnenolone. StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue Protocols Product Specific Protocols IF protocol for STAR antibody 67130-1-Ig Download protocol WB protocol for STAR antibody 67130-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Seminiferous tubule-inspired coaxial bioprinting-derived extracellular vesicles restore Leydig cell steroidogenesis through modulation of Wnt4/β-catenin signaling.
Journal: J Nanobiotechnology | Authors: Jialin Wu - Maternal Bisphenol S Exposure Impairs Testicular Development and Sperm Function in Male Offspring by Disrupting the Immune-Endocrine Network.
Journal: Small | Authors: Bin Li | Species: mouse | Application: IF - High matrix stiffness triggers testosterone decline in aging males by disrupting stem Leydig cell pool homeostasis
Journal: Cell Rep | Authors: Jiayu Huang - Saffron extract alleviates D-gal-induced late-onset hypogonadism by activating the PI3K-Akt-Nrf2 signaling pathway
Journal: J Ethnopharmacol | Authors: Hao Liu | Species: mouse | Application: WB,IF - Semaglutide Alleviates Ovary Inflammation via the AMPK/SIRT1/NF‑κB Signaling Pathway in Polycystic Ovary Syndrome Mice
Journal: Drug Des Devel Ther | Authors: Mei Liu | Species: mouse | Application: IF - Melatonin orchestrates cAMP-PKA signaling to alleviate zearalenone-impaired the estradiol synthesis in mammal ovary.
Journal: Int Immunopharmacol | Authors: Qiao Li | Species: mouse | Application: WB - Mechanism of the traditional Chinese medicine SMBJ alleviates diabetes mellitus-induced Leydig cell dysfunction in rats testes.
Journal: Sci Rep | Authors: Wenxiu Zhang | Species: rat | Application: WB,IHC - Gut-ovary axis and multiomic insights into PCOS in a DHEA-induced rat model.
Journal: Sci Rep | Authors: Zhi Chen | Species: rat | Application: WB - Reproductive effects of pubertal exposure to neonicotinoid thiacloprid in immature male mice
Journal: Toxicol Appl Pharmacol | Authors: Yong Zou | Species: mouse | Application: WB,IHC - Neuregulin 4 improves white adipose tissue inflammation in mice with polycystic ovary syndrome.
Journal: Peptides | Authors: Xi Wang - Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis.
Journal: Andrology | Authors: Shuning Yuan | Species: mouse | Application: WB - SP600125 decreases cAMP/PKA-dependent steroid production through ATF4/DDIT3 activation in MA-10 Leydig cells
Journal: Mol Cell Endocrinol | Authors: Audrey Basque | Species: mouse | Application: WB - SP600125 decreases cAMP/PKA-dependent steroid production through ATF4/DDIT3 activation in MA-10 Leydig cells
Journal: Mol Cell Endocrinol | Authors: Audrey Basque | Species: mouse | Application: WB - Impacts of elevated temperature on morphology, oxidative stress levels, and testosterone synthesis in ex vivo cultured porcine testicular tissue
Journal: Theriogenology | Authors: Kai Wang | Species: pig | Application: IF
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