SERPINE2 Monoclonal antibody 66203-1-Ig proteintech
$149.00
In stock
SKU
66203-1-Ig
| Catalog Number | 66203-1-Ig |
| Synonyms | GDN, Glia derived nexin, Peptidase inhibitor 7, PI 7, PI7, PN 1, PN1, PN-1, PNI, Protease nexin 1, Protease nexin I, Serpin E2, SERPINE2 |
| Host | Mouse |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF/ICC, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | hTERT-RPE1 cells, HEK-293 cells, C6 cells, Neuro-2a cells, U-87 MG cells, U-251 cells |
| Tested Applications — Positive IHC detected in | human placenta tissue, human testis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Tested Applications — Positive IF/ICC detected in | HEK-293 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Positive WB detected in | hTERT-RPE1 cells, HEK-293 cells, C6 cells, Neuro-2a cells, U-87 MG cells, U-251 cells |
| Positive IHC detected in | human placenta tissue, human testis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | HEK-293 cells |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag1830 Product name: Recombinant human SERPINE2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 28-397 aa of BC015663 Sequence: EELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINK Predict reactive species |
| Full Name | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| Calculated Molecular Weight | 44 kDa |
| Observed Molecular Weight | 44 kDa |
| GenBank Accession Number | BC015663 |
| Gene Symbol | SERPINE2 |
| Gene ID (NCBI) | 5270 |
| RRID | AB_2881594 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | P07093 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for SERPINE2 antibody 66203-1-Ig | Download protocol |
| IHC protocol for SERPINE2 antibody 66203-1-Ig | Download protocol |
| WB protocol for SERPINE2 antibody 66203-1-Ig | Download protocol |
| human,mouse | WB,IF Adv Mater Glycated ECM Derived Carbon Dots Inhibit Tumor Vasculogenic Mimicry by Disrupting RAGE Nuclear Translocation and Its Interaction With HMGB1 Authors - Shaoting Zheng View Article |
| mouse | WB,IHC Theranostics Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma Authors - Lu-Ning Qin View Article |
| human | IHC Oncol Lett Expression pattern of human SERPINE2 in a variety of human tumors. Authors - Ying Yang View Article |
| rat | IF J Cardiovasc Dev Dis Multi-Omics Identification of Biomarkers for High-Altitude Pulmonary Hypertension. Authors - Zhe Chen View Article |
| Citations | 8 |
| Dilutions | WB : 1:5000-1:50000 IHC : 1:50-1:500 IF/ICC : 1:200-1:800 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1E11F12 |
| Conjugation | Unconjugated |
SERPINE2 also called protease nexin-1 or glial-derived neurite promoting factor, is a member of the serine protease inhibitor (SERPIN) superfamily. It would be a potent inhibitor of the urokinase-plasminogen activator (uPA), tissue-type PA (tPA), thrombin, trypsin, factor Xia, and prostasin. SERPINE2 is widely expressed in various tissues, including endothelial cells, fibroblasts, smooth muscle cells, tumor cells, glial cells, neurons, and placental cells. Protocols Product Specific Protocols IF protocol for SERPINE2 antibody 66203-1-Ig Download protocol IHC protocol for SERPINE2 antibody 66203-1-Ig Download protocol WB protocol for SERPINE2 antibody 66203-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Glycated ECM Derived Carbon Dots Inhibit Tumor Vasculogenic Mimicry by Disrupting RAGE Nuclear Translocation and Its Interaction With HMGB1
Journal: Adv Mater | Authors: Shaoting Zheng | Species: human,mouse | Application: WB,IF - Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma
Journal: Theranostics | Authors: Lu-Ning Qin | Species: mouse | Application: WB,IHC - BAP31 Promotes Tumor Cell Proliferation by Stabilizing SERPINE2 in Hepatocellular Carcinoma.
Journal: Front Cell Dev Biol | Authors: Xiyang Zhang | Species: human | Application: WB - Integrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B biomarkers
Journal: Sci Rep | Authors: Haishun Qu | Species: human | Application: IHC - Expression pattern of human SERPINE2 in a variety of human tumors.
Journal: Oncol Lett | Authors: Ying Yang | Species: human | Application: IHC - Multi-Omics Identification of Biomarkers for High-Altitude Pulmonary Hypertension.
Journal: J Cardiovasc Dev Dis | Authors: Zhe Chen | Species: rat | Application: IF - Multi-Omics Identification of Biomarkers for High-Altitude Pulmonary Hypertension.
Journal: J Cardiovasc Dev Dis | Authors: Zhe Chen | Species: rat | Application: IF - Expression pattern of human SERPINE2 in a variety of human tumors.
Journal: Oncol Lett | Authors: Ying Yang | Species: human | Application: IHC
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