DHPS Polyclonal antibody 11184-1-AP proteintech

$149.00
In stock
SKU
11184-1-AP
Catalog No.SizePrice (USD)
11184-1-AP-20UL20 μL$149.00
11184-1-AP-150UL150 μL$449.00
Catalog Number11184-1-AP
SynonymsDHS, DS, EC:2.5.1.46, MIG13
HostRabbit
Reactivityhuman, mouse, rat
FormLiquid
FormulationPBS, Azide, Glycerol
ApplicationsWB, IHC, IF, IP, ELISA
ApplicationsWB, IP, ELISA
Host / IsotypeRabbit / IgG
Tested Applications — Positive WB detected inHeLa cells, LNCaP cells
Tested Applications — Positive IP detected inNIH/3T3 cells
Recommended Dilutions — Western Blot (WB)WB : 1:200-1:1000
Recommended Dilutions — Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Positive WB detected inHeLa cells, LNCaP cells
Positive IP detected inNIH/3T3 cells
Western Blot (WB)WB : 1:200-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Tested Reactivityhuman, mouse, rat
Cited Reactivityhuman, mouse
ClassPolyclonal
TypeAntibody
ImmunogenCatNo: Ag1646 Product name: Recombinant human DHPS protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-369 aa of BC014016 Sequence: MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED Predict reactive species
Full Namedeoxyhypusine synthase
Calculated Molecular Weight41 kDa
Observed Molecular Weight35-40 kDa
GenBank Accession NumberBC014016
Gene SymbolDHPS
Gene ID (NCBI)1725
RRIDAB_2877751
ConjugateUnconjugated
Purification MethodAntigen affinity purification
UNIPROT IDP49366
Storage BufferPBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
IF protocol for DHPS antibody 11184-1-APDownload protocol
IP protocol for DHPS antibody 11184-1-APDownload protocol
WB protocol for DHPS antibody 11184-1-APDownload protocol
humanIHC Cancer Lett Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene. Authors - Alain P. Gobert View Article
mouse,humanIF Res Sq Epithelial Hypusination Regulates Helicobacter pylori-induced Gastric Inflammation. Authors - Alain P Gobert View Article
human, mouseIF Res Sq A gene therapy strategy for Deoxyhypusine Synthase (DHPS) syndrome. Authors - Carolina Nunes Santo KO Validated View Article
Citations6
DilutionsWB : 1:200-1:1000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB
IsotypeIgG
ClonalityPolyclonal
Clone Number-
ConjugationUnconjugated

DHPS(Deoxyhypusine synthase) catalyzes the conversion of lysine to deoxyhypusine residue on the eukaryotic initiation factor 5A (eIF-5A) precursor using spermidine as the substrate. It belongs to the deoxyhypusine synthase family. This protein has 3 isoforms produced by alternative splicing. Protocols Product Specific Protocols IF protocol for DHPS antibody 11184-1-AP Download protocol IP protocol for DHPS antibody 11184-1-AP Download protocol WB protocol for DHPS antibody 11184-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols

Publications

  1. Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke.
    Journal: BMC Med | Authors: Takaki Hiwasa | Species: human | Application: IHC
  2. Analysis of the effect of hypusination in myeloid cells on colitis and colitis-associated cancer
    Journal: Heliyon | Authors: Alain P Gobert | Species: mouse,human | Application: IF
  3. Epithelial hypusination regulates Helicobacter pylori-induced gastric inflammation.
    Journal: Amino Acids | Authors: Alain P. Gobert | Species: mouse,human | Application: IF
  4. A gene therapy strategy for Deoxyhypusine Synthase (DHPS) syndrome.
    Journal: Res Sq | Authors: Carolina Nunes Santo KO Validated | Species: human, mouse | Application: IF
  5. Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene.
    Journal: Cancer Lett | Authors: Alain P. Gobert | Species: human | Application: IHC

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