DYRK1B Polyclonal antibody 12240-1-AP proteintech
$149.00
In stock
SKU
12240-1-AP
| Catalog Number | 12240-1-AP |
| Synonyms | DYRK1B, Minibrain related kinase, MIRK, Mirk protein kinase |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse testis tissue, HeLa cells, human colon tissue, human heart tissue, mouse skeletal muscle tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:4000 |
| Positive WB detected in | mouse testis tissue, HeLa cells, human colon tissue, human heart tissue, mouse skeletal muscle tissue |
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag2883 Product name: Recombinant human DYRK1B protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 38-343 aa of BC018751 Sequence: RDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKA Predict reactive species |
| Full Name | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| Calculated Molecular Weight | 629 aa, 69 kDa |
| Observed Molecular Weight | 57 kDa |
| GenBank Accession Number | BC018751 |
| Gene Symbol | DYRK1B |
| Gene ID (NCBI) | 9149 |
| RRID | AB_2093803 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y463 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for DYRK1B antibody 12240-1-AP | Download protocol |
| human | WB Am J Physiol Cell Physiol MicroRNA-9 enhances the transactivation of nuclear factor of activated T cells by targeting KPNB1 and DYRK1B. Authors - Yan Zeng View Article |
| Citations | 2 |
| Dilutions | WB : 1:1000-1:4000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
DYRK1B(dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B) is also named as MIRK. It is a member of the dyrk/minibrain family of serine/threonine kinases that mediate the transition from growth to differentiation in lower eukaryotes and mammals(PMID:15546868). DYRK1B functions as a transcriptional coactivator that is activated by co-expressed MKK3, a MAP kinase that also can activate p38 MAP kinase(PMID:14500717). The DYRK1B splice variants found in each muscle tissue exhibit approximate molecular weights of 70 and 75 kDa(PMID:12902328). It has 3 isoforms produced by alternative splicing of the molecular weight of 65-69 kDa. Protocols Product Specific Protocols WB protocol for DYRK1B antibody 12240-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- MicroRNA-9 enhances the transactivation of nuclear factor of activated T cells by targeting KPNB1 and DYRK1B.
Journal: Am J Physiol Cell Physiol | Authors: Yan Zeng | Species: human | Application: WB - Discovery of Arenarine D and its active derivatives as a novel lead targeting DYRK1B/MYH9 in hepatic fibrosis.
Journal: Eur J Med Chem | Authors: Chen Wang
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