FKBP8 Monoclonal antibody 66690-1-Ig proteintech
$149.00
In stock
SKU
66690-1-Ig
| Catalog Number | 66690-1-Ig |
| Synonyms | FKBP-38, FKBP38, FKBP 8, FKBP 38, FK506-binding protein 8 |
| Host | Mouse |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF/ICC, CoIP, ELISA |
| Applications | WB, IHC, IF/ICC, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | Jurkat cells, HEK-293 cells, HeLa cells, HepG2 cells, NIH/3T3 cells, RAW 264.7 cells |
| Tested Applications — Positive IHC detected in | human hypothalamus tissue, mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Tested Applications — Positive IF/ICC detected in | A431 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:10000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:250-1:1000 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Positive WB detected in | Jurkat cells, HEK-293 cells, HeLa cells, HepG2 cells, NIH/3T3 cells, RAW 264.7 cells |
| Positive IHC detected in | human hypothalamus tissue, mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | A431 cells |
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Immunohistochemistry (IHC) | IHC : 1:250-1:1000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag1649 Product name: Recombinant human FKBP8 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-355 aa of BC009966 Sequence: MGQPPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN Predict reactive species |
| Full Name | FK506 binding protein 8, 38kDa |
| Calculated Molecular Weight | 45 kDa |
| Observed Molecular Weight | 53 kDa |
| GenBank Accession Number | BC009966 |
| Gene Symbol | FKBP8 |
| Gene ID (NCBI) | 23770 |
| RRID | AB_2882044 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | Q14318 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for FKBP8 antibody 66690-1-Ig | Download protocol |
| IHC protocol for FKBP8 antibody 66690-1-Ig | Download protocol |
| WB protocol for FKBP8 antibody 66690-1-Ig | Download protocol |
| mouse | WB PLoS One Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation Authors - Michael O Isei KD Validated View Article |
| human | CoIP J Biol Chem Lysine demethylase KDM1A promotes cell growth via FKBP8-BCL2 axis in hepatocellular carcinoma Authors - Suli Lv View Article |
| Citations | 3 |
| Dilutions | WB : 1:2000-1:10000 IHC : 1:250-1:1000 IF/ICC : 1:200-1:800 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1C1G12 |
| Conjugation | Unconjugated |
FK506 binding protein 8 (FKBP8), is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP8 does not seem to have PPIase/rotamase activity, which is different from other members of this family. The active form of FKBP8 may play a role in the regulation of apoptosis. FKBP8 has 3 isoforms produced by alternative splicing. Protocols Product Specific Protocols IF protocol for FKBP8 antibody 66690-1-Ig Download protocol IHC protocol for FKBP8 antibody 66690-1-Ig Download protocol WB protocol for FKBP8 antibody 66690-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation
Journal: bioRxiv | Authors: Michael O Isei KD Validated | Species: mouse | Application: WB,IF - Lysine demethylase KDM1A promotes cell growth via FKBP8-BCL2 axis in hepatocellular carcinoma
Journal: J Biol Chem | Authors: Suli Lv | Species: human | Application: CoIP
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