PITX2 Monoclonal antibody 67201-1-Ig proteintech
$149.00
In stock
SKU
67201-1-Ig
| Catalog Number | 67201-1-Ig |
| Synonyms | 1E3B1, ALL1-responsive protein ARP1, ARP1, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor |
| Host | Mouse |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IF, ELISA |
| Applications | WB, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | rat brain tissue, HEK-293 cells, mouse brain tissue, rat cerebellum tissue, mouse cerebellum tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Positive WB detected in | rat brain tissue, HEK-293 cells, mouse brain tissue, rat cerebellum tissue, mouse cerebellum tissue |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | mouse, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag27924 Product name: Recombinant human PITX2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-286 aa of BC013998 Sequence: MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNS Predict reactive species |
| Full Name | paired-like homeodomain 2 |
| Calculated Molecular Weight | 36 kDa |
| Observed Molecular Weight | 30 kDa |
| GenBank Accession Number | BC013998 |
| Gene Symbol | PITX2 |
| Gene ID (NCBI) | 5308 |
| RRID | AB_2882494 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | Q99697 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for PITX2 antibody 67201-1-Ig | Download protocol |
| rat | WB,IF PLoS One ATRA influences the differentiation and fusion of myoblasts by regulating Rarα/Pitx2, leading to abnormal development of the pelvic floor muscles (PFMs) in fetal rats. Authors - Hanbin Zhao View Article |
| mouse | WB Aging (Albany NY) D-galactose causes sinoatrial node dysfunction: from phenotype to mechanism Authors - Heng Zhang KD Validated View Article |
| Kenzo (Verified Customer) (03-28-2024) | Worked well for immunofluorescence in mouse heart tissues. Applications: Immunofluorescence Primary Antibody Dilution: 1:200 Cell Tissue Type: Mouse heart |
| Citations | 4 |
| Dilutions | WB : 1:5000-1:50000 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1E3B1 |
| Conjugation | Unconjugated |
PITX2 belongs to the bicoid class of homeodomain transcription factors, which play essential roles in embryonic development. Various PITX2 isoforms are involved in a wide variety of developmental programs, including left-right signaling. It controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, PITX2 is involved in the expansion of muscle progenitors. In addition, it may play a role in the proper localization of asymmetric organs such as the heart and stomach. PITX2 can be bound by some other proteins, and are part of a much larger atrial transcriptional complex. This antibody specifically recognizes isoform PTX2C. Protocols Product Specific Protocols WB protocol for PITX2 antibody 67201-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Journal: Oral Dis | Authors: Yi Yang KD Validated | Species: rat | Application: WB - Single-cell Atlas of Developing Mouse Palates Reveals Cellular and Molecular Transitions in Periderm Cell Fate
Journal: Genomics Proteomics Bioinformatics | Authors: Wenbin Huang | Species: mouse | Application: IF - ATRA influences the differentiation and fusion of myoblasts by regulating Rarα/Pitx2, leading to abnormal development of the pelvic floor muscles (PFMs) in fetal rats.
Journal: PLoS One | Authors: Hanbin Zhao | Species: rat | Application: WB,IF - D-galactose causes sinoatrial node dysfunction: from phenotype to mechanism
Journal: Aging (Albany NY) | Authors: Heng Zhang KD Validated | Species: mouse | Application: WB
Product Documents
Reviews
Write Your Own Review