Dematin Polyclonal antibody 16808-1-AP proteintech
$149.00
In stock
SKU
16808-1-AP
| Catalog Number | 16808-1-AP |
| Synonyms | EPB49, EPB 49, DMTN, Dematin actin-binding protein |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, ELISA |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | human red blood cells, rat brain tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:10000 |
| Positive WB detected in | human red blood cells, rat brain tissue |
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag10300 Product name: Recombinant human EPB49 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-405 aa of BC017445 Sequence: MERLQKQPLTSPGSVSPSRDSSVPGSPSSIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWADSRSPGIISQASAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRRGAEEEEEEEDDDSGEEMKALRERQREELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLHQGTSKSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF Predict reactive species |
| Full Name | erythrocyte membrane protein band 4.9 (dematin) |
| Calculated Molecular Weight | 405 aa, 46 kDa |
| Observed Molecular Weight | 48-52 kDa |
| GenBank Accession Number | BC017445 |
| Gene Symbol | Dematin |
| Gene ID (NCBI) | 2039 |
| RRID | AB_2277891 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q08495 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for Dematin antibody 16808-1-AP | Download protocol |
| human | WB Front Med Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome Authors - Yashuang Yang View Article |
| human,mouse | WB,IHC,IF Exp Cell Res Dematin inhibits glioblastoma malignancy through RhoA-mediated CDKs downregulation and cytoskeleton remodeling. Authors - Mengying Wang View Article |
| Citations | 2 |
| Dilutions | WB : 1:2000-1:10000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Dematin (band 4.9) is a widely expressed cytoskeletal protein which regulates cell shape and cell migration. It is best known for its role within the red blood cell (RBC), where it has been localized to the spectrin-actin junctions of RBC membrane. Dematin has a 48 kDa subunit containing a headpiece domain and a 52 kDa subunit. Protocols Product Specific Protocols WB protocol for Dematin antibody 16808-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome
Journal: Front Med | Authors: Yashuang Yang | Species: human | Application: WB - Dematin inhibits glioblastoma malignancy through RhoA-mediated CDKs downregulation and cytoskeleton remodeling.
Journal: Exp Cell Res | Authors: Mengying Wang | Species: human,mouse | Application: WB,IHC,IF
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