EPOR Recombinant monoclonal antibody, PBS Only (Capture) 83056-4-PBS proteintech
$699.00
In stock
SKU
83056-4-PBS
| Catalog Number | 83056-4-PBS |
| Synonyms | 230117G3, EPO R, EPO-R, erythropoietin receptor |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | IF/ICC, Sandwich ELISA, Indirect ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag33956 Product name: Recombinant human EPOR protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 25-250 aa of NM_000121.4 Sequence: APPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDP Predict reactive species |
| Full Name | erythropoietin receptor |
| Calculated Molecular Weight | 55 kDa |
| GenBank Accession Number | NM_000121.4 |
| Gene Symbol | EPOR |
| Gene ID (NCBI) | 2057 |
| RRID | AB_3670782 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P19235 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 230117G3 |
| Conjugation | Unconjugated |
Erythropoietin (EPO) receptor (EPOR) is a glycoprotein that belongs to the type I superfamily of single-transmembrane cytokine receptors. It consists of an extracellular domain that binds to the EPO ligand, a transmembrane domain and an intracellular domain. The interaction of EPO and EPOR triggers the activation of several signaling pathways that induce erythropoiesis, including JAK2/STAT5, PI3K/AKT, and MAPK (PMID: 34281163). EPOR is present on erythroid progenitor cells and has also been detected on a wide variety of non-hematopoietic cells (PMID: 36233351).
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